2026-10-19T01:04:18Zhttps://ebyu-rdlopen.rawdatalibrary.net/oai/request

oai:ebyu-rdlopen.rawdatalibrary.net:ebyu/120642026-10-18T21:14:18Zopenairedrivercom_ebyu_10000col_ebyu_10001

The Relationship Between Vitamin-D Deficiency and Protein Oxidation Among Obese ChildrenSurucu Kara, IlknurMertoglu, CumaSiranli, GülsahArslan, Yusuf KemalGok, GamzeErel, Ozcanchildrenobesepre-obesethiol-disulfide homeostasisvitamin DAdolescentBiomarkersChildDisulfidesFemaleHumansMaleOxidative StressPediatric ObesitySerum AlbuminSulfhydryl CompoundsVitamin D DeficiencyVitaminsdisulfideinsulinischemia modified albuminthiolbiological markerthiol derivativevitaminArticlecontrolled studyhomeostasishumanhypertriglyceridemiaAim: The aim of the study is to examine the relationship between obesity, Vitamin-D deficiency, and protein oxidation. Methods: Thiol-disulfide homeostasis, Vitamin-D, ischemia modified albumin, insulin, and lipid levels were compared among obese, pre-obese and normal-weight healthy children. Results: A total of 136 children (69 boys and 67 girls) were included in the study. The vitamin-D levels of obese children were lower than those of pre-obese and normal weight (p < 0.05). In the normal weight group, total thiol and native thiol were lower in the pubertal period than in adolescence; were higher in those with sufficient Vitamin-D level than those with insufficient and deficient Vitamin-D (p < 0.05). Vitamin-D level was lower in pre-obese girls than boys (p < 0.05). Those with high triglycerides had high disulfide/total thiol, disulfide, and disulfide/native thiol and low native thiol/total thiol (p < 0.05). Conclusion: Thiol-disulfide homeostasis is negatively affected by low vitamin D levels, pubertal period and high triglyceride levels. © 2023 Taylor & Francis Group, LLC.Taylor and Francis Ltd.2023Articlehttps://rdlopen.rawdatalibrary.net/r/ebyu/12064https://doi.org/10.1080/15513815.2023.21830261551-3815enFetal and Pediatric Pathologyinfo:eu-repo/semantics/openAccessinfo:eu-repo/semantics/articlehttps://ebyu-rdlopen.rawdatalibrary.net/tr/items/ebyu/12064