2026-10-19T01:08:05Zhttps://ebyu-rdlopen.rawdatalibrary.net/oai/requestoai:ebyu-rdlopen.rawdatalibrary.net:ebyu/123612026-10-18T20:33:53Zopenairedrivercom_ebyu_10000col_ebyu_10001Isolation of Undescribed Biflavonoid from Potamogeton pusillus L. and Antidiabetic Activity PropertiesAkşit, Hüseyinantidiabetic propertiesbiflavonoidPotamogeton pusillus Lsulfated flavonesα-glucosidaseacarbosealpha glucosidaseflavone derivativephytochemicalplant extractPotamogeton pusillus extractrosmarinic acidunclassified drugantidiabetic activityantioxidant activityArticlebacterium isolationbiomasscarbon nuclear magnetic resonancechemical structurecolumn chromatographyhigh performance liquid chromatographyIC50liquid chromatography-mass spectrometrynonhumannuclear magnetic resonanceproton nuclear magnetic resonancespectrophotometrythin layer chromatographytime of flight mass spectrometryA phytochemical study on the Potamogeton pusillus L. led to the isolation and identification of a novel biflavonoid, pusillin A (1) with known seven compounds, including rosmarinic acid (2), luteolin-7-sulfate (3), eriodictyol-7-sulfate (4), chrysoeriol-7-sulfate (5), eriodictyol (5), luteolin (7) and chrysoeriol (8). Their structures were elucidated based on spectrometric analysis, including LC-Q-TOF/MS and NMR. All compounds were screened for in vitro antidiabetic activity using the spectrophotometric method. Sulfated flavones (1, 3, 4, and 5) exhibited prominent α-glucosidase inhibitory activity, and compounds 2, 6, 7, and 8 showed moderate inhibitory activities. All isolates were reported for the first time from the plant material. © 2023, ACG Publications. All rights reserved.ACG Publications2023Articlehttps://rdlopen.rawdatalibrary.net/r/ebyu/12361https://doi.org/10.25135/rnp.385.2211.26281307-6167enRecords of Natural Productsinfo:eu-repo/semantics/openAccessinfo:eu-repo/semantics/articlehttps://ebyu-rdlopen.rawdatalibrary.net/tr/items/ebyu/12361