2026-10-19T02:47:38Zhttps://ebyu-rdlopen.rawdatalibrary.net/oai/requestoai:ebyu-rdlopen.rawdatalibrary.net:ebyu/127372026-10-18T21:13:23Zopenairedrivercom_ebyu_10000col_ebyu_10001High Fetuin-A Levels in Children with Celiac DiseaseKurt, NezahatOzgeris, Fatma BetulVolkan, BurcuGul, Mehmet AliCayir, Atillabone mineral densityCeliac diseaseFetuin-AObjective: Fetuin-A is a multifunctional non-collagen protein that plays a role in bone mineralization. Celiac disease is a chronic inflammatory disorder of the small intestine due to exposure to gluten. In this research, it was aimed to investigate levels of Fetuin-A and its relationship with bone mineral density in children with celiac disease. Materials and Methods: The study was conducted on 59 children with celiac and 29 healthy children. The celiac disease group was composed of three groups, newly diagnosed, gluten-free diet compliant and, non-gluten-free diet compliant patients. Serum Fetuin-A concentrations were measured by an enzyme-linked immunosorbent assay kit. Measurement of bone mineral density was performed a dual-energy x-ray absorptiometry. Results: Serum Fetuin-A levels were 136.85 ± 38.09 µg/L and 112.95 ± 44.39 µg/L in the celiac disease and healthy control groups, respectively. There was a statistically significant difference between groups in levels of serum Fetuin-A (P <.05). A significant positive correlation was observed between serum Fetuin-A and bone mineral density Z-score in the celiac patients. Conclusion: Increased Fetuin-A levels and positive correlation between Fetuin-A and bone mineral density in children with celiac disease suggest that Fetuin-A may be a biomarker for celiac disease. © 2022, AVES. All rights reserved.AVES2022Articlehttps://rdlopen.rawdatalibrary.net/r/ebyu/12737https://doi.org/10.5152/eurasianjmed.2022.212931308-8734enEurasian Journal of Medicineinfo:eu-repo/semantics/openAccessinfo:eu-repo/semantics/articlehttps://ebyu-rdlopen.rawdatalibrary.net/tr/items/ebyu/12737