2026-10-18T23:16:12Zhttps://ebyu-rdlopen.rawdatalibrary.net/oai/requestoai:ebyu-rdlopen.rawdatalibrary.net:ebyu/143412026-10-18T21:14:21Zopenairedrivercom_ebyu_10000col_ebyu_10001The effects of intravitreal ranibizumab, aflibercept or dexamethasone implant injections on intraocular pressure changesKarakurt, YucelUcak, TurgayTaslı, GamzeAgcayazı, Burcuİcel, ErelYılmaz, HayatiAxial length, eyeIntraocular pressureIntravitreal injectionsAgedAged, 80 and overAngiogenesis InhibitorsAntibodies, Monoclonal, HumanizedDexamethasoneFemaleHumansMacular DegenerationMaleMiddle AgedPostoperative CareRanibizumabReceptors, Vascular Endothelial Growth FactorRecombinant Fusion ProteinsRetrospective StudiesVascular Endothelial Growth Factor AVisual Acuityafliberceptangiogenesis inhibitorfusion proteinmonoclonal antibodyvasculotropin Avasculotropin receptoradultage related macular degenerationangiographyanterior eye chamber depthBackground: The aim of this study was to compare the alterations in intraocular pressure (IOP) values during the early postoperative period after intravitreal ranibizumab, aflibercept, or dexamethasone implant injections. Material/Methods: In this retrospective study, a total of 188 patients were grouped into 3 groups: the ranibizumab group, the aflibercept group, and the dexamethasone group. Ocular axial length (AXL) and anterior chamber depth (ACD) were measured in the pre-injection period. IOP was measured just before the injection at 1 minute,10 minutes, 1 hour, 1 day, and 1 month after injection. Results: There was a transient peak in the ranibizumab group and the aflibercept group at 1 minute that started to decrease at 10 minutes and IOP values returned to preoperative values at approximately 1 hour. Similar alterations were also determined for the dexamethasone group with a lesser increase noted. In the correlation analysis, only alterations in IOP levels at 1 minute were negatively correlated with preoperative AXL values. There was not any correlation between preoperative AXL or ACD values and IOP alterations at any other time points. Conclusions: There was a sudden, transient increase in IOP values after intravitreal ranibizumab or aflibercept injections; which return to normal values in a short time without requirement of any medical treatments. This transient peak was determined to be negatively correlated with the preoperative AXL. © Med Sci Monit,.International Scientific Information, Inc.2018Articlehttps://rdlopen.rawdatalibrary.net/r/ebyu/14341https://doi.org/10.12659/msm.9109231234-1010enMedical Science Monitorinfo:eu-repo/semantics/openAccessinfo:eu-repo/semantics/articlehttps://ebyu-rdlopen.rawdatalibrary.net/tr/items/ebyu/14341