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oai:ebyu-rdlopen.rawdatalibrary.net:ebyu/144462026-10-18T21:14:22Zopenairedrivercom_ebyu_10000col_ebyu_10001

Obesity-related metabolic and endocrine disorders diagnosed during postoperative follow-up of slipped capital femoral epiphysisUcpunar, HanifiCamurcu, Ismet YalkinDuman, SerdaUcpunar, EsraSofu, HakanBayhan, Avni IlhanAdolescentChildDiabetes Mellitus, Type 2DyslipidemiasFemaleHumansMaleObesityPostoperative PeriodPrevalenceRetrospective StudiesSlipped Capital Femoral EpiphysesVitamin D DeficiencyYoung Adultalanine aminotransferaseaspartate aminotransferasecholesterolcreatinineglucosehemoglobin A1chigh density lipoprotein cholesterolliothyroninelow density lipoprotein cholesterolthyrotropintriacylglycerolureavitamin Dadolescent obesityalanine aminotransferase blood levelArticleBackground and purpose — Patients with slipped capital femoral epiphysis (SCFE) are phenotypically overweight or obese and may therefore require clinical follow-up of obesity-related disorders. We evaluated obesity-related disorders such as dyslipidemia, type 2 diabetes mellitus (DM), and vitamin-D deficiency during the postoperative period in patients with SCFE. Patients and methods — 51 patients who were operated and followed-up for SCFE and 62 healthy adolescents without SCFE (control group) were included in this retrospective study. Patients’ BMI, serum lipid profile (total cholesterol, LDL-C, HDL-C, triglyceride), fasting blood glucose, HbA1c, and serum vitamin D levels were evaluated. Results — At the time of surgery, 45 patients in the SCFE group were overweight or obese (BMI >25). At the latest follow-up, 42 patients in the SCFE group and 53 patients in the control group were overweight/obese. Abnormal serum lipid profile and ratio of total dyslipidemia were similar between the groups. 8 patients had abnormal HbA1c levels in the SCFE group and mean HbA1c levels were significantly higher in the SCFE group (p = 0.03). All patients and controls had low levels of vitamin D. Interpretation — Although serum lipid profile and vitamin D levels were detected as similar in SCFE and control groups, the potential risk of type 2 DM identified via abnormal HbA1c levels was significantly higher in patients with SCFE. We recommend that patients diagnosed with SCFE should be considered as potential candidates for type 2 DM; thus follow-up after surgical treatment should include not only orthopedic outcomes but also evaluation of future risk for DM. © 2018 The Author(s). Published by Taylor & Francis on behalf of the Nordic Orthopedic Federation.Taylor and Francis Ltd2018Articlehttps://rdlopen.rawdatalibrary.net/r/ebyu/14446https://doi.org/10.1080/17453674.2018.14451671745-3674enActa Orthopaedicainfo:eu-repo/semantics/openAccessinfo:eu-repo/semantics/articlehttps://ebyu-rdlopen.rawdatalibrary.net/tr/items/ebyu/14446