2026-10-19T00:27:22Zhttps://ebyu-rdlopen.rawdatalibrary.net/oai/request

oai:ebyu-rdlopen.rawdatalibrary.net:ebyu/145682026-10-18T21:14:27Zopenairedrivercom_ebyu_10000col_ebyu_10001

Bilirubin Levels and Thrombus Burden in Patients with ST-Segment Elevation Myocardial InfarctionHamur, HikmetDuman, HakanBakirci, Eftal MuratKucuksu, ZaferDemirelli, SelamiKalkan, KamuranDegirmenci, Husnubilirubinmyocardial infarctionthrombus burdenAdultAgedAged, 80 and overBiomarkersChi-Square DistributionCoronary ThrombosisCross-Sectional StudiesFemaleHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioRisk FactorsSeverity of Illness IndexST Elevation Myocardial Infarctionacetylsalicylic acidbeta adrenergic receptor blocking agentbilirubin glucuronidecalcium channel blocking agentclopidogreldipeptidyl carboxypeptidase inhibitorheme oxygenasehepariniopromidebiological markerWe investigated whether serum bilirubin level (a marker of heme oxygenase activity) is a predictor of thrombus burden in patients with acute myocardial infarction. Patients (n = 229; male 72.9%; mean age 63 ± 13.4 years) who were admitted with ST-segment elevation myocardial infarction (STEMI) were enrolled. Patients were divided into 2 groups. Group 1 was defined as low thrombus burden and group 2 was defined as high thrombus burden. Patients with high thrombus burden had higher total bilirubin levels (14.4 [4.3-22.9] vs 7.7 [2.4-20.3] μmol/L, P ≤.001), (0.84 [0.25-1.34] vs 0.45 [0.14-1.19] mg/dL P ≤.001) and direct bilirubin levels (3.1 [2.1-8.4] vs 1.7 [0.5-6.5] μmol/L, P ≤.001), (0.18 [0.03-0.49] vs 0.10 [0.03-0.38] mg/dL, P ≤.001). At multivariate analysis, total bilirubin (odds ratio: 1.05, 95% confidence interval: 1.03-1.08, P ≤.001) was the independent predictor of high thrombus burden. In conclusion, total bilirubin level is independently associated with high thrombus burden in patients with STEMI. © SAGE Publications.SAGE Publications Inc.2016Articlehttps://rdlopen.rawdatalibrary.net/r/ebyu/14568https://doi.org/10.1177/00033197156038990003-3197enAngiologyinfo:eu-repo/semantics/openAccessinfo:eu-repo/semantics/articlehttps://ebyu-rdlopen.rawdatalibrary.net/tr/items/ebyu/14568