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oai:ebyu-rdlopen.rawdatalibrary.net:ebyu/150082026-10-18T21:14:22Zopenairedrivercom_ebyu_10000col_ebyu_10001

Estimation of the prevalence and distribution of HPV genotypes and identification of related risk factors among Turkish womenKulhan, MehmetKulhan, Nur G.Seven, YaseminNayki, Umit A.Nayki, CenkAta, NahitUlug, PasaCervical smearsHPV genotypingHuman papillomavirus DNA testsadultArticlecancer screeningcontrolled studyfemalehumanHuman papillomavirus type 16Human papillomavirus type 18Human papillomavirus type 31Human papillomavirus type 33Human papillomavirus type 35Human papillomavirus type 39Human papillomavirus type 40Human papillomavirus type 42Human papillomavirus type 43Human papillomavirus type 44Human papillomavirus type 45Human papillomavirus type 51Human papillomavirus type 52Human papillomavirus type 53Human papillomavirus type 54Human papillomavirus type 56Human papillomavirus type 58Human papillomavirus type 59Human papillomavirus type 61Human papillomavirus type 68Human papillomavirus type 72Aim of the study: The present study aims to estimate the prevalence and distribution of HPV genotypes and identify related risk factors among Turkish women. Material and methods: 11 624 Turkish women attending our gynaecological clinic and expressing a desire for access to cervical cancer screening were assessed during the years 2014-2016. Cervical specimens were collected and transported using the HC2 HPV DNA Collection Device (consisting of a cervical brush and digene Specimen Transport Medium). Results: Among these 11 624 individuals, positive HPV test results were obtained for 325 (2.79%), and negative results were observed for 11 299 (97.2%). The vast majority of patients were between the 3rd and 5th decades and the mean age of the patients was 44 ±9.12 (range 27-66). Among the HPV-positive women, 205 were positive for a single HPV type (205/325 = 63.1% of HPV infections; 205/11624 = 1.76% of all samples) and 120 were positive for multiple types (120/325 = 36.9% of HPV infections; 120/11624 = 1.03% of all samples). The four most prevalent high-risk types were HPV 16, 31, 51 and 52, with frequencies of 11.25%, 7.83%, 6.06% and 3.16%, respectively. Conclusions: There appears to be geographic variation in the distribution of HPV genotypes. In this study, the four most prevalent high-risk types were HPV 16, 31, 51 and 52, with frequencies of 11.25%, 7.83%, 6.06% and 3.16%, respectively.Termedia Publishing House Ltd.2017Articlehttps://rdlopen.rawdatalibrary.net/r/ebyu/15008https://doi.org/10.5114/wo.2017.695911428-2526enWspolczesna Onkologiainfo:eu-repo/semantics/openAccessinfo:eu-repo/semantics/articlehttps://ebyu-rdlopen.rawdatalibrary.net/tr/items/ebyu/15008