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The investigation of damage in the muscle tissue with the oxidant/antioxidant balance and the extent of postmortem DNA damage in ratsOzturk, CengizTalip Sener, MustafaSener, EbruYilmaz, IsmayilAkcay, FatihSuleyman, HalisAntioxidantDNA damageMuscleOxidantPost-mortem intervalRatThe relationship of the extent of DNA damage and certain components of the oxidant/antioxidant balance in rat femoral muscle tissue with the post-mortem intervals was investigated and examined by making direct comparison with the histopathological findings. The results have shown that the oxidant/antioxidant balance in the striated muscle tissue to remain constant at the 0 hours post-mortem; to shift mildly in favour of the oxidants at 2 hours post-mortem; to shift moderately in favour of the oxidants at 3 hours post-mortem; and, to shift severely in favour of the oxidants at 4 and 5 hours post-mortem. The amount of DNA damaged products was detected to increase at 4 and 5 post-mortem hours when the oxidant/antioxidant balance became severely shifted. The biochemical findings were found to be in full accordance with the histopathological findings. The above-mentioned findings indicate that DNA becomes subjected to degradation at the hours after post-mortem when the oxidants are strongly predominate.2013Articlehttps://rdlopen.rawdatalibrary.net/r/ebyu/158531097-8135enLife Science Journalinfo:eu-repo/semantics/openAccessinfo:eu-repo/semantics/articlehttps://ebyu-rdlopen.rawdatalibrary.net/tr/items/ebyu/15853