2026-10-19T01:05:10Zhttps://ebyu-rdlopen.rawdatalibrary.net/oai/request

oai:ebyu-rdlopen.rawdatalibrary.net:ebyu/171082026-10-18T20:49:19Zopenairedrivercom_ebyu_10000col_ebyu_10001

Antioxidant Activity and Theoretical Profile of Novel 2,4,6-Triarylpyridine Derivatives Based on Syringaldehydeakşit, HüseyinŞİMŞEK, SamedAkşit, Zeynepatahan, alparslanMUSATAT, AHMAD BADREDDINAlbayrak, Esra NurKimyaOrganikBiyokimya ve Moleküler BiyolojiEight novel 2,4,6-triarylpyridines derived from syringaldehyde were designed and synthesized via a multicomponent one-step preparation method. Those compounds were evaluated for their antioxidant activities comparing with known reference compounds. In the studied series, toluyl, methoxyphenyl, and pyridinyl-bearing derivatives exhibited considerable antioxidant activities. Meanwhile, using the B3LYP theory and SVP, TZVP basis sets, a comprehensive theoretical quantum computing approach for the synthesized compounds was established and electronic structure descriptive parameters called Fukui indices describing the radical scavenging potential were determined. Finally, the structure-activity relationship was revealed by comparing the theoretical and experimental outputs. As a result, the potential antioxidant activity of the studied compounds was also supported by a theoretical approach.2024Articlehttps://rdlopen.rawdatalibrary.net/r/ebyu/17108https://doi.org/10.29130/dubited.1320385trDüzce Üniversitesi Bilim ve Teknoloji Dergisiinfo:eu-repo/semantics/openAccessinfo:eu-repo/semantics/articlehttps://ebyu-rdlopen.rawdatalibrary.net/tr/items/ebyu/17108