2026-10-19T01:08:16Zhttps://ebyu-rdlopen.rawdatalibrary.net/oai/request

oai:ebyu-rdlopen.rawdatalibrary.net:ebyu/186252026-10-18T20:56:40Zopenairedrivercom_ebyu_10000col_ebyu_10001

Persimmon (Diospyros Kaki L.) Alleviates Ethanol-Induced Gastric Ulcer in RatsEraslan, Ersentanyeli, ayhanAkdemir, Fazile Nur Ekinciguler, mustafa canTOKAY, ErdemKURT, NezahatCapanoglu, EsraBozhuyuk, Mehmet RamazanÖZKAN, GülayTıbbi Araştırmalar DeneyselGastroenteroloji ve HepatolojiObjective: The worldwide incidence of a gastric ulcer is high, most often as a result of useof nonsteroidal anti-inflammatory drugs, excessive alcohol consumption, or Helicobacterpylori infection. An ethanol-based gastric ulcer model in rats was used to examine the effectof persimmon (Diospyros kaki L.) extract as a potential form of treatment.Methods: Two dosages of persimmon extract were applied in a gastric ulcer model createdwith 5 mL/kg ethanol in Wistar albino rats. Histopathological and biochemical methods wereused to assess any gastroprotective effects.Results: Persimmon extract significantly decreased the level of the cytokines interleukin(IL)-10, IL-6, tumor necrosis factor alpha (TNF-α) and IL-1 beta. Caspase-3 and nuclearfactor kappa B expression was also significantly reduced.Conclusion: Persimmon fruit extract demonstrated a gastroprotective effect in an ethanol-based gastric ulcer model in rats.2021Articlehttps://rdlopen.rawdatalibrary.net/r/ebyu/18625https://doi.org/10.14744/scie.2020.945462587-0998enSouthern Clinics of Istanbul Eurasiainfo:eu-repo/semantics/openAccessinfo:eu-repo/semantics/articlehttps://ebyu-rdlopen.rawdatalibrary.net/tr/items/ebyu/18625