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oai:ebyu-rdlopen.rawdatalibrary.net:ebyu/202852026-10-18T21:12:07Zopenairedrivercom_ebyu_10000col_ebyu_10001

Synthesis and Biological Evaluation of New 2-Ethoxy-6-[(4,5- dihydro-1H-1,2,4-triazol-5-one-4-yl)iminomethyl]phenyl 4-nitro-benzoate DerivativesKOL, ÖZLEM GÜRSOYALBAYRAK, ÖNDERAlkan, Muzafferyüksek, HaydarMANAP, SevdaKARDAŞ, Farukbeytur, muratKimyaUygulamalıTıbbiBiyokimya ve Moleküler BiyolojiIn the present study, 3-alkyl(aryl)-4-amino-4,5-dihydro-1H-1,2,4-triazol-5-ones (1) reacted with 3-ethoxy-2-(4- nitrobenzoxy)-benzaldehyde (2) to afford 2-ethoxy-6-[(3-alkyl/aryl-4,5-dihydro-1H-1,2,4-triazol-5-one-4-yl) iminomethyl]phenyl 4-nitrobenzoates (3). The structures of new nine compounds were established from the elemental analyses, IR, 1 H NMR and 13C NMR spectral data. The synthesized compounds were analyzed for their in vitro potential antioxidant activities in three different methods. In addition, these new compounds were screened for their antimicrobial activities.2017Articlehttps://rdlopen.rawdatalibrary.net/r/ebyu/20285https://doi.org/10.15671/hjbc.2017.1481303-5002enHacettepe Journal of Biology and Chemistryinfo:eu-repo/semantics/openAccessinfo:eu-repo/semantics/articlehttps://ebyu-rdlopen.rawdatalibrary.net/tr/items/ebyu/20285