Paediatric liver biopsies: A single-centre experience in Erzincan Binali Yıldırım University

ArticleAçık Erişim

Özet

Introduction: Liver biopsies are the main method in the diagnosis and treatment of paediatric liver pathologies. Major complication rates of paediatric liver biopsies range from 0% to 6.6% in the literature and minor complication rates range from 0% to 25%. In this study, we aimed to review the complications, indications and results of percutaneous core liver biopsies with paediatric sonography in a tertiary care centre by an interventional radiologist. Methods: We retrospectively evaluated the results, indications and complications of paediatric liver biopsies performed in our tertiary health centre between January 2017 and December 2020. Biopsies were performed with a 16G semi-automatic needle in 17 patients (29.8%) and with an 18G semi-automatic needle in 40 patients (70.2%). Biopsies were performed only with local anaesthesia in patients older than 12 years; in younger patients, it was performed under general anaesthesia. Results: Fifty-eight liver biopsies were obtained from 57 children (34 males, 23 females). The most common indications were elevated liver enzymes (33 patients), cholestasis (14 patients), and adiposity and metabolic problems (6 patents). The most common pathological diagnoses were chronic hepatitis (33 patients) and steatosis (10 patients). Major complication in the form of symptomatic subcapsular haematoma developed after liver biopsy performed with 18G needle in only one patient (1.8%). Conclusions: As previously stated in the literature, percutaneous biopsies performed by interventional radiologists in paediatric patients under the guidance of sonography can be used in diagnosis and treatment; the complication rate is low and it is a safe method. © The Author(s) 2023.

Anahtar Kelimeler

RDL Kalıcı Bağlantı (PID)
https://rdlopen.rawdatalibrary.net/r/ebyu/11887Resmi atıflarda kullanılan kalıcı adres
DOI
https://doi.org/10.1177/1742271x231157634Yayıncı resmi DOI adresi
Tam Kayıt
AlanDeğerDil
dc.contributor.authorKazci, Omer
dc.contributor.authorKadirhan, Ozlem
dc.contributor.authorUner, Cigdem
dc.contributor.authorKaravas, Erdal
dc.contributor.authorUcan, Berna
dc.contributor.authorAydin, Sonay
dc.date.accessioned2026-10-18T20:26:52.545392450Z
dc.date.available2026-10-18T20:26:52.545392450Z
dc.date.issued2024
dc.description.abstractIntroduction: Liver biopsies are the main method in the diagnosis and treatment of paediatric liver pathologies. Major complication rates of paediatric liver biopsies range from 0% to 6.6% in the literature and minor complication rates range from 0% to 25%. In this study, we aimed to review the complications, indications and results of percutaneous core liver biopsies with paediatric sonography in a tertiary care centre by an interventional radiologist. Methods: We retrospectively evaluated the results, indications and complications of paediatric liver biopsies performed in our tertiary health centre between January 2017 and December 2020. Biopsies were performed with a 16G semi-automatic needle in 17 patients (29.8%) and with an 18G semi-automatic needle in 40 patients (70.2%). Biopsies were performed only with local anaesthesia in patients older than 12 years; in younger patients, it was performed under general anaesthesia. Results: Fifty-eight liver biopsies were obtained from 57 children (34 males, 23 females). The most common indications were elevated liver enzymes (33 patients), cholestasis (14 patients), and adiposity and metabolic problems (6 patents). The most common pathological diagnoses were chronic hepatitis (33 patients) and steatosis (10 patients). Major complication in the form of symptomatic subcapsular haematoma developed after liver biopsy performed with 18G needle in only one patient (1.8%). Conclusions: As previously stated in the literature, percutaneous biopsies performed by interventional radiologists in paediatric patients under the guidance of sonography can be used in diagnosis and treatment; the complication rate is low and it is a safe method. © The Author(s) 2023.
dc.identifier.doi10.1177/1742271x231157634
dc.identifier.eissn1743-1344
dc.identifier.endpage10
dc.identifier.issn1742-271X
dc.identifier.issue1
dc.identifier.pmcidPMC10836225
dc.identifier.pmid38314022
dc.identifier.scopus2-s2.0-85151073104
dc.identifier.startpage4
dc.identifier.urihttps://rdlopen.rawdatalibrary.net/r/ebyu/11887
dc.identifier.volume32
dc.identifier.wosWOS:000956504400001
dc.language.isoen
dc.publisherSAGE Publications Ltd
dc.relation.ispartofUltrasound
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectcomplications
dc.subjectinterventional radiology
dc.subjectPaediatric
dc.subjectpercutaneous liver biopsy
dc.subjectultrasound
dc.subjectbilirubin
dc.subjecthemoglobin
dc.subjectmidazolam
dc.subjectparacetamol
dc.subjectropivacaine
dc.subjectanastomosis leakage
dc.subjectarterial blood pressure measurement
dc.subjectArticle
dc.subjectbile duct atresia
dc.subjectbile leakage
dc.subjectbiliary structure
dc.subjectbiliary tract hemorrhage
dc.subjectbleeding
dc.subjectblood cell count
dc.subjectbreathing rate
dc.subjectchild
dc.subjectcholestasis
dc.subjectchronic hepatitis
dc.subjectclinical evaluation
dc.subjectcoagulation parameters
dc.subjectcold compression
dc.subjectcontrolled study
dc.subjectdemography
dc.subjectdisease severity assessment
dc.subjectDoppler flowmetry
dc.titlePaediatric liver biopsies: A single-centre experience in Erzincan Binali Yıldırım University
dc.typeArticle
dspace.entity.typePublication
rdl.citation.scopus0
rdl.citation.wos0
rdl.departmentDepartment of Radiology, Faculty of Medicine, Erzincan Binali Yıldırım University, Erzincan, Turkey.
rdl.oa.statusgreen
rdl.source.indexSCOPUS
rdl.source.indexWOS
rdl.source.indexPUBMED
rdl.wos.indexEmerging Sources Citation Index (ESCI)