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Serum Inflammation Biomarkers in Patients with Keratoconus

ArticleAçık Erişim

Özet

Purpose: To evaluate inflammation-sensitive parameters, namely the neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), eosinophil count, erythrocyte distribution width (RDW), and CRP/albumin ratio in patients with keratoconus (KC). Methods: Thirty-five patients with KC and 30 healthy people (control group) were included in the study. Complete blood count measurements were performed in all subjects, and NLR, PLR and the CRP/albumin ratio were calculated. Results: NLR was determined as 2.01 ± 0.53 in patients with KC and 1.97 ± 0.41 in the control group. PLR was 146.20 ± 23.32 in the KC group and 121.45 ± 31.75 in the healthy group. The CRP/albumin ratio was determined as 0.33 ± 0.09 in the KC group and 0.29 ± 0.11 in the healthy group. Conclusion: Although no significant difference was found between the groups in terms of NLR, CRP/albumin ratio and RDW levels, PLR was significantly higher in the KC group. © 2020 Taylor & Francis Group, LLC.

Anahtar Kelimeler

CRP/albumin ratioinflammationKeratoconusneutrophil-to-lymphocyte ratioplatelet-to-lymphocyte ratioAdolescentAdultAlbuminsBiomarkersBlood Cell CountBlood PlateletsCase-Control StudiesEosinophilsErythrocyte IndicesFemaleHumansLeukocyte CountLymphocytesMaleNeutrophilsReceptors, ImmunologicYoung AdultalbuminC reactive proteinalbuminoidbiological markerCRP protein, humanimmunoglobulin receptoranterior eye chamber angleanterior eye chamber depth
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Tam Kayıt
AlanDeğerDil
dc.contributor.authorBozkurt, Erdinc
dc.contributor.authorUcak, Turgay
dc.date.accessioned2026-10-18T20:28:09.378384679Z
dc.date.available2026-10-18T20:28:09.378384679Z
dc.date.issued2021
dc.description.abstractPurpose: To evaluate inflammation-sensitive parameters, namely the neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), eosinophil count, erythrocyte distribution width (RDW), and CRP/albumin ratio in patients with keratoconus (KC). Methods: Thirty-five patients with KC and 30 healthy people (control group) were included in the study. Complete blood count measurements were performed in all subjects, and NLR, PLR and the CRP/albumin ratio were calculated. Results: NLR was determined as 2.01 ± 0.53 in patients with KC and 1.97 ± 0.41 in the control group. PLR was 146.20 ± 23.32 in the KC group and 121.45 ± 31.75 in the healthy group. The CRP/albumin ratio was determined as 0.33 ± 0.09 in the KC group and 0.29 ± 0.11 in the healthy group. Conclusion: Although no significant difference was found between the groups in terms of NLR, CRP/albumin ratio and RDW levels, PLR was significantly higher in the KC group. © 2020 Taylor & Francis Group, LLC.
dc.identifier.doi10.1080/09273948.2020.1741648
dc.identifier.eissn1744-5078
dc.identifier.endpage1167
dc.identifier.issn0927-3948
dc.identifier.issue6
dc.identifier.pmid32255702
dc.identifier.scopus2-s2.0-85083590447
dc.identifier.startpage1164
dc.identifier.urihttps://rdlopen.rawdatalibrary.net/r/ebyu/13314
dc.identifier.volume29
dc.identifier.wosWOS:000526285400001
dc.language.isoen
dc.publisherTaylor and Francis Ltd.
dc.relation.ispartofOcular Immunology and Inflammation
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCRP/albumin ratio
dc.subjectinflammation
dc.subjectKeratoconus
dc.subjectneutrophil-to-lymphocyte ratio
dc.subjectplatelet-to-lymphocyte ratio
dc.subjectAdolescent
dc.subjectAdult
dc.subjectAlbumins
dc.subjectBiomarkers
dc.subjectBlood Cell Count
dc.subjectBlood Platelets
dc.subjectCase-Control Studies
dc.subjectEosinophils
dc.subjectErythrocyte Indices
dc.subjectFemale
dc.subjectHumans
dc.subjectLeukocyte Count
dc.subjectLymphocytes
dc.subjectMale
dc.subjectNeutrophils
dc.subjectReceptors, Immunologic
dc.subjectYoung Adult
dc.subjectalbumin
dc.subjectC reactive protein
dc.subjectalbuminoid
dc.subjectbiological marker
dc.subjectCRP protein, human
dc.subjectimmunoglobulin receptor
dc.subjectanterior eye chamber angle
dc.subjectanterior eye chamber depth
dc.titleSerum Inflammation Biomarkers in Patients with Keratoconus
dc.typeArticle
dspace.entity.typePublication
rdl.citation.scopus28
rdl.citation.wos28
rdl.departmentFaculty of Medicine, Department of Ophthalmology, Erzincan University, Erzincan, Turkey.
rdl.source.indexSCOPUS
rdl.source.indexWOS
rdl.source.indexPUBMED
rdl.wos.indexScience Citation Index Expanded (SCI-EXPANDED)