Microsurgery Results in Vestibular Schwannoma Patients: Retrospective Clinical Study

ArticleAçık Erişim

Özet

Objective: Nowadays due to developing imaging techniques, vestibular schwannoma cases are monitored more frequently. In this study, the results of the patients who underwent surgery in the Department of Neurosurgery, Istanbul University Istanbul School of Medicine were retrospectively evaluated. Methods: Radiological and clinical findings of 18 patients with vestibular schwannoma diagnosed in our clinic from 2012 to 2017 were evaluated. After describing the possible treatment methods of the disease in detail, oral and written informed consent was obtained from all of them. Results: In our study, 18 patients, consisting of 13 women and 5 males, were examined. Eleven patients were found with a mass diameter below 3 cm, and seven patients were found with mass diameter above 3 cm. All patients underwent mass resection with retrosigmoid craniotomy. Total resection was performed in 11 patients, and subtotal resection was done in 7 patients. In seven patients with total resection (63.6%), a newly developed facial paresis was observed. The newly developed glossopharyngeal nerve paresis was observed in three patients (27.2%), and also abducens nerve paresis in three patients (27.2%). The facial nerve was preserved at a rate of 42% in tumors larger than 3 cm in size. The CSF fistula developed in one patient (5.5%); hydrocephalus developed in one patient (5.5%). Conclusion: In cases of vestibular schwannoma, microsurgery, radiosurgery, and wait/follow approaches are monitored. Although gold is standard microsurgery in tumors sized above 3 cm, the treatment plan for tumors under 3 cm in size is controversial. In this study, postoperative facial paresis was developed in all patients with total resection, which were below the mass size of 3 cm. The fact that the abducens and glossopharyngeal nerve paresis in patients with total resection have been seen less frequently in patients with subtotal resection is a factor that can affect the decision of total-subtotal resection. Therefore, the treatment plan should be taken into consideration (total resection/subtotal resection + radiosurgery) considering the existing neuromonitoring facilities in tumors larger than 3 cm in size.

Anahtar Kelimeler

RDL Kalıcı Bağlantı (PID)
https://rdlopen.rawdatalibrary.net/r/ebyu/17020Resmi atıflarda kullanılan kalıcı adres
DOI
https://doi.org/10.5152/jarem.2019.2226Yayıncı resmi DOI adresi
Tam Kayıt
AlanDeğerDil
dc.contributor.authorCan, Halil
dc.contributor.authorDolgun, Muge
dc.contributor.authorOzgen, Utku
dc.contributor.authorGomleksiz, Cengiz
dc.contributor.authorDiren, Furkan
dc.contributor.authorAydoseli, Aydin
dc.contributor.authorAras, Yavuz
dc.contributor.authorSencer, Altay
dc.date.accessioned2026-10-18T20:42:57.830426241Z
dc.date.available2026-10-18T20:42:57.830426241Z
dc.date.issued2019
dc.description.abstractObjective: Nowadays due to developing imaging techniques, vestibular schwannoma cases are monitored more frequently. In this study, the results of the patients who underwent surgery in the Department of Neurosurgery, Istanbul University Istanbul School of Medicine were retrospectively evaluated. Methods: Radiological and clinical findings of 18 patients with vestibular schwannoma diagnosed in our clinic from 2012 to 2017 were evaluated. After describing the possible treatment methods of the disease in detail, oral and written informed consent was obtained from all of them. Results: In our study, 18 patients, consisting of 13 women and 5 males, were examined. Eleven patients were found with a mass diameter below 3 cm, and seven patients were found with mass diameter above 3 cm. All patients underwent mass resection with retrosigmoid craniotomy. Total resection was performed in 11 patients, and subtotal resection was done in 7 patients. In seven patients with total resection (63.6%), a newly developed facial paresis was observed. The newly developed glossopharyngeal nerve paresis was observed in three patients (27.2%), and also abducens nerve paresis in three patients (27.2%). The facial nerve was preserved at a rate of 42% in tumors larger than 3 cm in size. The CSF fistula developed in one patient (5.5%); hydrocephalus developed in one patient (5.5%). Conclusion: In cases of vestibular schwannoma, microsurgery, radiosurgery, and wait/follow approaches are monitored. Although gold is standard microsurgery in tumors sized above 3 cm, the treatment plan for tumors under 3 cm in size is controversial. In this study, postoperative facial paresis was developed in all patients with total resection, which were below the mass size of 3 cm. The fact that the abducens and glossopharyngeal nerve paresis in patients with total resection have been seen less frequently in patients with subtotal resection is a factor that can affect the decision of total-subtotal resection. Therefore, the treatment plan should be taken into consideration (total resection/subtotal resection + radiosurgery) considering the existing neuromonitoring facilities in tumors larger than 3 cm in size.
dc.identifier.doi10.5152/jarem.2019.2226
dc.identifier.eissn2147-1894
dc.identifier.endpage85
dc.identifier.issn2146-6505
dc.identifier.issue2
dc.identifier.startpage80
dc.identifier.urihttps://rdlopen.rawdatalibrary.net/r/ebyu/17020
dc.identifier.volume9
dc.identifier.wosWOS:000462341500004
dc.language.isotr
dc.publisherAVES
dc.relation.ispartofJOURNAL OF ACADEMIC RESEARCH IN MEDICINE-JAREM
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectVestibular schwannoma
dc.subjectcerebellopontine angle tumor
dc.subjectcranial nerve paresis
dc.subjectradiosurgery
dc.subjectGAMMA-KNIFE SURGERY
dc.subjectFRACTIONATED STEREOTACTIC RADIOTHERAPY
dc.subjectACOUSTIC NEUROMA
dc.subjectHEARING
dc.subjectMANAGEMENT
dc.subjectMedicine, General & Internal
dc.subjectGeneral & Internal Medicine
dc.titleMicrosurgery Results in Vestibular Schwannoma Patients: Retrospective Clinical Study
dc.typeArticle
dspace.entity.typePublication
rdl.citation.trdizin0
rdl.citation.wos0
rdl.departmentÖzel Kuruluş
rdl.departmentERZİNCAN BİNALİ YILDIRIM ÜNİVERSİTESİ
rdl.departmentİSTANBUL ÜNİVERSİTESİ
rdl.departmentBİRUNİ ÜNİVERSİTESİ
rdl.departmentT.C. SAĞLIK BAKANLIĞI
rdl.oa.statusopen
rdl.source.indexWOS
rdl.source.indexTRDIZIN
rdl.wos.indexEmerging Sources Citation Index (ESCI)