Ugurlu, A.; Icel, E.

Introduction: In this study, we aimed to evaluate the possible relationship between the neutrophil-to-lymphocyte, monocyte-to-lymphocyte and platelet-to-lymphocyte ratio and retinopathy of prematurity (ROP). Material and Method: The data of 348 patients who applied to Erzincan University Ophthalmology Unit for screening the retinopathy of prematurity were analysed retrospectively. One hundred sixty seven patients who were collected CBC samples within the first 72 hours after delivery and who met the inclusion criteria were included in the study. Infants with a gestational age of ≤35 week were screened for ROP. Pateints were divided into two groups. Group 1 was involved the patients with the diagnosis of ROP and group 2 was involved the normal patients (no ROP). The levels of NLR, PLR and MLR were determined in two groups. Results: Fifty-nine patients who were detected ROP are in group 1 and 108 patients who were not seen ROP are in group 2 in the study. The mean gestational age at birth of the patients was 30.4±2.1 [26-34] weeks in group 1 and 33.7±1.7 [27-35] weeks in group 2 (P=0.004). The mean gestational weigth at birth was 1927.2±158.4 [1690-2300] gram in group 1 and 2169.1±283.1 [1750-3100] gram in group 2. (P<0.001) With the result of logistic regression analysis, gestational age [Odds Ratio(OR): 0.531, 95%CI: 0.388-0.726, P<0.001], NLR [OR:34.849, 95%CI: 2.091-580.779, P=0.013] and PLR [OR: 1.067, 95%CI: 1.034-1.110, P<0.001] were detected the independent risk factors for ROP. Conclusion: Our study revealed that higher NLR and PLR which are evaluated with in first 72h after birth is an independent predictor of ROP.

Kara, İ.; Koc, U.

Coffin-Siris syndrome is a rare syndrome diagnosed by clinical features such as mental retardation, growth retardation, absence or hypoplasia of the fifth distal phalanx, different facial features and supported by genetic testing. Stercoral colitis is an inflammatory colitis, which is usually caused by an increase in intraluminal pressure in stool material stuck in colon segments, which is rarely seen in patients with chronic constipation and may result in perforation, shock and death. Our 11-year-old male patient was brought to the emergency department with the complaint of inability to walk and the patient was diagnosed with stercoral colitis with appropriate evaluation. This is the first case in the literature in which coexistence of Coffin-Siris syndrome and Stercoral colitis were seen.