Ertekin, Ayfer; Demir, Recep; Özdemir, Gokhan; Özel, Lutfi; Özyildirim, Ercan; Ulvi, Hizir

The relationships between the prevalence of AD, socio-demographic characteristics, and other chronic diseases were researched within the population aged 65 and over living in Erzurum city center. The study was realized between June of 2010 and July of 2011. It involved 455 people over age 65 living in Erzurum city center. The Mini-Mental State Examination and Daily Living Scale were applied to participants. A total of 455 people participated in the study. AD was detected in 29 people. Twenty-one participants were female, and eight were male. The prevalence of AD was calculated to be 6.4%. According to the results of a logistic regression analysis, the AD prevalence detection rate in the a 75-84 age group was ten times greater than in the 65-74 age group, and the rate in the 85 and over group was 36 times greater than in the 65-74 age group. AD is more common in women than in men. The rate increases 4.1-fold among those with AD diabetes mellitus disease, 3.9-fold among those with Parkinson's disease, 2.6-fold among those with heart disease, and 4.2-fold among those with dementia in their families. AD prevalence for those age of 65 and over was shown to be 6.4% in our study. The risk of AD increases 17-fold with increasing age. The risk of developing AD also increases in cases of chronic diseases.

Erdur, Fatih Mehmet; Turkmen, Kultigin; Kayikcioglu, Hatice; Ozcicek, Fatih; Toker, Aysun; Ozbek, Orhan; Turk, Suleyman; Tonbul, Halil Zeki

Vascular calcifcation and increased oxidative stress are commonly seen in patients with end-stage renal disease (ESRD). Nitrotyrosine is one of the end products of nitric oxide metabolism and is accepted as an indicator of oxidative stress. Nitrotyrosine levels have been found to be high in ESRD patients. The aim of our study is to investigate the relation between coronary artery calcifcation and oxidative stress in peritoneal dialysis (PD) and hemodialysis (HD) patients. 46 PD and 34 HD patients are included in the study. Coronary artery calcifcation scoring (CACS) is made by multi slice computed tomography. Patients are divided into 4 groups according to their CACS values as Group 1 (CACS: 0), Group 2 (CACS:1-99), Group 3 (CACS:100-399) and Group 4 (CACS: ≥400). Serum nitrotyrosine levels were measured. Nitrotyrosine levels were signifcantly increased in HD patients compared to PD patients. Nitrotyrosine levels were found to be elevated in accordance with increased CACS in PD patients. However, we could not fnd this relationship in HD patients. There might be an important relationship between CACS and oxidative stress in PD patients.

Ertekin, Ayfer; Demir, Recep; Özdemir, Gökhan; Özel, Lütfi; Özyıldırım, Ercan; Ulvi, Hızır

The relationships between the prevalence of AD, socio-demographic characteristics, and other chronic diseases were researched within the population aged 65 and over living in Erzurum city center. The study was realized between June of 2010 and July of 2011. It involved 455 people over age 65 living in Erzurum city center. The Mini-Mental State Examination and Daily Living Scale were applied to participants. A total of 455 people participated in the study. AD was detected in 29 people. Twenty-one participants were female, and eight were male. The prevalence of AD was calculated to be 6.4%. According to the results of a logistic regression analysis, the AD prevalence detection rate in the a 75-84 age group was ten times greater than in the 65-74 age group, and the rate in the 85 and over group was 36 times greater than in the 65-74 age group. AD is more common in women than in men. The rate increases 4.1-fold among those with AD diabetes mellitus disease, 3.9-fold among those with Parkinson’s disease, 2.6-fold among those with heart disease, and 4.2-fold among those with dementia in their families. AD prevalence for those age of 65 and over was shown to be 6.4% in our study. The risk of AD increases 17-fold with increasing age. The risk of developing AD also increases in cases of chronic diseases.