Aesculus hippocastanum L.

Medicinal plants have been used in the treatment of various diseases since ancient times. Aesculus hippocastanum (horse chestnut) is a popular herb recognized worldwide and used in treatment. The seed extract of the plant contains phytocompounds such as flavonoids, hydroxycoumarins, proanthocyanidins, sterols, tannins, amino acids, and triterpenoid saponin glycosides. Studies have confirmed that Hippocastani semen extracts and pure substance have various activities, including anti-inflammatory, antibacterial, antifungal, antiviral, antiangiogenic (vascular protection), anti-obesity, antioxidative, antidiabetic, antidiabetic neuropathy, hepatoprotective, anticoagulant, antihematoma, antigenotoxic, anti-infertility, and cytotoxic properties. Due to the activity of A. hippocastanum extracts and their bioactive compounds, this herb may be useful as an alternative therapy for a variety of ailments. © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022.