Urinary System Infection at Diabetes Mellitus and Obesity Patients: A Retrospective Evaluation

Aim: In this study, it was aimed to investigate the distribution of isolated pathogens, the resistance rates of these pathogens to antimicrobials, presence of glycosuria and pyuria in patients with diabetes mellitus (DM) and obesity in adult and pediatric endocrine outpatient clinics with urinary system infections. Material and Methods: Between January 2012 and February 2014, records of 107 patients with DM and obesity in Duzce University Medical Faculty Hospital Adult and Pediatric Endocrine outpatient clinics were retrospectively reviewed. Biochemical/microbiological laboratory results of urine specimens taken from these patients were evaluated. Fisher Exact and Pearson Chi-Square tests were used with statistical evaluation of SPSS 22.0 program. Results: Thirty-two (70%) of the patients were children, 75 (30%) are adults; 84 (78.5%) were female, 23 (21.5%) were male, mean of ages 25.1±23. Number of patients with diabetes and obesity were 76 (71.0%) and 31 (29.0%), respectively. Bacterial growth occurred 28 (26%) of urine cultures (23 (30.2%) of patients with DM, 5 (16.1%) of patients with obesity). E. coli was detected most frequently as causative agent. In patients with pyuria and glycosuria, more bacterial growth were detected and statistically significant correlation was found between pyuria and bacterial growth, but no significant relationship was found with glycosuria. Conclusion: Although glycosuria may increase the risk of infection, it may not be a determining parameter alone, but patients should be assessed considering the current risk; it has also been found that there is a strong relationship between the presence of the pyuria and urinary tract infection. However, it is considered appropriate to start antibiotic treatment according to the causative agent and sensitivity profile isolated in urine culture rather than to start empirical treatment according to the complete urine analysis result.