Recommendations of the International Society of Geriatric Oncology on skin cancer management in older patients
Özet
Introduction: Non-melanoma skin cancer (NMSC) is becoming ever more prevalent among older adults. However, older adults with NMSC are often underrepresented in clinical trials and guidelines on effective management is still unclear. The International Society of Geriatric Oncology (SIOG) created a multi-disciplinary task force to explore the potential in developing practical guidelines for the treatment of older patients with basal cell carcinoma (BCC) and skin (cutaneous) squamous cell carcinoma (cSCC). Materials and Methods: A systematic literature search to identify relevant and up-to-date literature on treatment of NMSC in older adults was conducted on various databases including MEDLINE, Embase, CINAHL, Cochrane, and PubMed. The resulting papers were discussed by an expert panel, leading to a consensus recommendation. Results: A total of 154 articles were identified for the expert panel to utilise in generating consensus recommendations. A major focus on geriatric assessment and management options including surgery, radiotherapy, systemic therapy, clinical monitoring, and medical/medicophysical therapy were reviewed for recommendations. Discussion: Patient age should not be the sole deciding factor in the management of patients with NMSC. Assessment from a multidisciplinary team (MDT) is crucial, and the decision-making process should consider the patient's lifestyle, needs, and expectations. A comprehensive geriatric assessment should also be considered. Patients should feel empowered to advocate for themselves and have their views considered a part of the MDT discussion. © 2023 Elsevier Ltd
Anahtar Kelimeler
Tam Kayıt
| Alan | Değer | Dil |
|---|---|---|
| dc.contributor.author | Rembielak, Agata | |
| dc.contributor.author | Yau, Thomas | |
| dc.contributor.author | Akagunduz, Baran | |
| dc.contributor.author | Aspeslagh, Sandrine | |
| dc.contributor.author | Colloca, Giuseppe | |
| dc.contributor.author | Conway, Aoife | |
| dc.contributor.author | Danwata, Falalu | |
| dc.contributor.author | del Marmol, Veronique | |
| dc.contributor.author | O'Shea, Chuck | |
| dc.contributor.author | Verhaert, Marthe | |
| dc.contributor.author | Zic, Rado | |
| dc.contributor.author | Livesey, Dan | |
| dc.date.accessioned | 2026-10-18T20:27:17.617415789Z | |
| dc.date.available | 2026-10-18T20:27:17.617415789Z | |
| dc.date.issued | 2023 | |
| dc.description.abstract | Introduction: Non-melanoma skin cancer (NMSC) is becoming ever more prevalent among older adults. However, older adults with NMSC are often underrepresented in clinical trials and guidelines on effective management is still unclear. The International Society of Geriatric Oncology (SIOG) created a multi-disciplinary task force to explore the potential in developing practical guidelines for the treatment of older patients with basal cell carcinoma (BCC) and skin (cutaneous) squamous cell carcinoma (cSCC). Materials and Methods: A systematic literature search to identify relevant and up-to-date literature on treatment of NMSC in older adults was conducted on various databases including MEDLINE, Embase, CINAHL, Cochrane, and PubMed. The resulting papers were discussed by an expert panel, leading to a consensus recommendation. Results: A total of 154 articles were identified for the expert panel to utilise in generating consensus recommendations. A major focus on geriatric assessment and management options including surgery, radiotherapy, systemic therapy, clinical monitoring, and medical/medicophysical therapy were reviewed for recommendations. Discussion: Patient age should not be the sole deciding factor in the management of patients with NMSC. Assessment from a multidisciplinary team (MDT) is crucial, and the decision-making process should consider the patient's lifestyle, needs, and expectations. A comprehensive geriatric assessment should also be considered. Patients should feel empowered to advocate for themselves and have their views considered a part of the MDT discussion. © 2023 Elsevier Ltd | |
| dc.description.sponsorship | This activity is supported by an independent medical education grant from Regeneron Pharmaceuticals, Inc. and Sanofi Genzyme, and Xstrahl . | |
| dc.identifier.doi | 10.1016/j.jgo.2023.101502 | |
| dc.identifier.issn | 1879-4068 | |
| dc.identifier.issue | 4 | |
| dc.identifier.pmid | 37080793 | |
| dc.identifier.scopus | 2-s2.0-85152909846 | |
| dc.identifier.startpage | 101502 | |
| dc.identifier.uri | https://rdlopen.rawdatalibrary.net/r/ebyu/12383 | |
| dc.identifier.volume | 14 | |
| dc.language.iso | en | |
| dc.publisher | Elsevier Ltd | |
| dc.relation.ispartof | Journal of Geriatric Oncology | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.subject | Basal cell carcinoma | |
| dc.subject | Cancer treatment | |
| dc.subject | Cutaneous squamous cell carcinoma | |
| dc.subject | Geriatric assessment | |
| dc.subject | Older patients | |
| dc.subject | Skin cancer | |
| dc.subject | Aged | |
| dc.subject | Carcinoma, Basal Cell | |
| dc.subject | Carcinoma, Squamous Cell | |
| dc.subject | Humans | |
| dc.subject | Radiation Oncology | |
| dc.subject | Skin Neoplasms | |
| dc.subject | cemiplimab | |
| dc.subject | fluorouracil | |
| dc.subject | imiquimod | |
| dc.subject | age | |
| dc.subject | Article | |
| dc.subject | brachytherapy | |
| dc.subject | cancer chemotherapy | |
| dc.subject | cancer immunotherapy | |
| dc.subject | cancer therapy | |
| dc.subject | clinical monitoring | |
| dc.subject | cryotherapy | |
| dc.subject | external beam radiotherapy | |
| dc.subject | follow up | |
| dc.subject | human | |
| dc.subject | Mohs micrographic surgery | |
| dc.subject | nursing care | |
| dc.subject | palliative therapy | |
| dc.subject | patient advocacy | |
| dc.title | Recommendations of the International Society of Geriatric Oncology on skin cancer management in older patients | |
| dc.type | Article | |
| dspace.entity.type | Publication | |
| rdl.citation.scopus | 19 | |
| rdl.department | Young SIOG Member, Department of Medical Oncology, Erzincan Binali Yıldrıım University Medical School, Erzincan, Turkey. | |
| rdl.source.index | SCOPUS | |
| rdl.source.index | PUBMED |
