Sürdürülebilir Kalkınma Amaçları
Yayınlar
- ArticleYalnız künye2013Primer Uterin Hidatik Kist: Olgu Sunumu
Karakeçili, Faruk; Uluğ, Paşa; Sayar, İlyas; Naykı Aslan, Ümit; Yıldırım, Yusuf; Peker, Kemal; Naykı, Cenk
Echinococcosis, which is caused by echinococcus granulosus, is also known as cystic hydatid disease, unilocular echinococcosis or cystic echinococcosis. Cystic echinococcosis is an alarming public health problem in some countries. Although the liver and lung are the organs involved most commonly by the disease, it may appear rarely in other tissues as a primary disease. Here, we present a 66-year-old patient who is invoved in farm work work. A Uterine multiseptate hydatid cyst was found on radiological investigations and the patient underwent surgery. A total hysterectomy was carried out. There were no postoperative complications. (Turkiye Parazitol Derg 2013; 37: 302-4)
RDL Kalıcı Kaydıİncele - ArticleYalnız künye2013Eş Zamanlı kolorektal karsinom ve ekinokok hastalığı: İki olgu sunumu
İnal, Abdullah; Peker, Kemal
Colorectal cancer (CRC) is currently the most common malignity of the gastrointestinal (GI) system in the world. CRC is the third most frequently diagnosed cancer in the U.S.A and it ranks third in cancer-related causes of death. Its etiology is complex, involving both environmental and genetic factors. Hydatid disease is an endemic disease, especially in eastern countries. E. granulosus and E. multilocularis are the most frequent types responsible for hydatidosis in human beings. Echinococcus larvae develop in cystic form, mostly in the liver or lungs. We presented two cases of rectum cancer who had co-existing liver echinococcus.
RDL Kalıcı Kaydıİncele - ArticleYalnız künye2013Anastomoz kaçağının endoskopik olarak fibrin glue ile tedavisi
Yılmaz, İsmayil; Peker, Kemal; Demiryılmaz, İsmail
Surgeons have been using sutures made up of different materials to reunite disrupted tissues, throughout centuries. But these materials may have certain disadvantages like foreign body reaction, infection, scarring, need for removal and cost. Their application is time-consuming and needs skill and experience. Whereas tissue adhesives is one of alternative to conventional suturing and has some additional advantages. The use of fibrin glue, as in concentrated human fibrinogen in combination with thrombin for hemostasis and tissue adhesion has been an important advance in a variety of surgical applications. The purpose of this study is to share our experience about fibrin glue.
RDL Kalıcı Kaydıİncele - ArticleYalnız künye2013İnvajinasyona sebep olan dev inflamatuar fibroid polip: Olgu sunumu
Yılmaz, İsmayil; Sekban, Nurdan; Yılmaz Postgil, Serpil; Albayrak, Yavuz; Peker, Kemal; Demiryılmaz, İsmail
İnvajinasyon proksimaldeki barsak parçasının distal parça içine girmesi ile karakterize bir klinik tablodur. Tüm invajinasyonların yalnızca %5'i erişkinde görülür. İnflamatuar fibroid polip gastrointestinal sistemin nadir görülen, en sık mide antrumundan köken almakla birlikte gastrointestinal sistemin her yerinde görülebilen lezyonudur. Yazımızda 42 yaşında terminal ileumda dev polipoid kitleye bağlı ileokolik invajinasyon gelişen ve malignite şüphesiyle terminal ileum rezeksiyonuyla beraber sağ hemikolektomi yapılan ve kitlenin patolojisi inflamatuar fibriod polip olarak değerlendirilen olgu sunulmaktadır
RDL Kalıcı Kaydıİncele - ArticleYalnız künye2013Endoscopic balloon dilatation for the treatment of mechanical intestinal obstruction secondary to colorectal anastomotic stenosis
Yılmaz, İsmayil; Peker, Kemal; Demiryılmaz, İsmail
İntestinal obstrüksiyon, intestinal içeriğin gastrointestinal sistem içinde distale doğru olan geçişinin, parsiyel ya da tam olarak engellenmesidir. İntestinal obstrüksiyon, acil karın ameliyatlarının önemli nedenlerinden biridir; uygun şekilde tedavi edilmediğinde yüksek oranda morbidite ve mortaliteye neden olabilmektedir. Günümüzde acil kolonoskopi, özellikle kolon kaynaklı akut mekanik intestinal obstrüksiyon vakalarının tanı ve tedavilerinde kullanılmaktadır. Biz burada revizyon cerrahisi sonrası anastomoz darlığı gelişen ve edoskopik dilatasyon yöntemi ile tedavi edilen bir vakayı taktim ettik. Anastomoz darlıklarında endoskopik dilatasyon, daha az invaziv, başarı şansı yüksek, komplikasyon oranları düşük ve tekrarlanabilir bir yöntemdir
RDL Kalıcı Kaydıİncele - ArticleAçık Erişim2013Concurrent Echinococcus Disease with Colorectal Carcinoma: Reports of Two Cases
Peker, Kemal; Inal, Abdullah
Colorectal cancer (CRC) is currently the most common malignity of the gastrointestinal (GI) system in the world. CRC is the third most frequently diagnosed cancer in the U.S.A and it ranks third in cancer-related causes of death. Its etiology is complex, involving both environmental and genetic factors. Hydatid disease is an endemic disease, especially in eastern countries. E. granulosus and E. multilocularis are the most frequent types responsible for hydatidosis in human beings. Echinococcus larvae develop in cystic form, mostly in the liver or lungs. We presented two cases of rectum cancer who had co-existing liver echinococcus.
RDL Kalıcı Kaydıİncele - ArticleAçık Erişim2013Post-Traumatic Pneumoscrotum: Case Report
Peker, Kemal; Güllü, Huriye; Sahin, Murat; Issin, Ahmet
Pneumoscrotum is a rare pathology that has received little attention in the literature, although a few cases have been presented with different causes. Etiological factors that can cause pneumoscrotum include the lungs, retroperitoneal sources, surgical procedures or infections with microorganisms producing gas. A 57-year-old man was admitted to the emergency department following a motorcycle accident. He had chest excoriations and a painless crepitant scrotum. In conclusion, subcutaneous emphysema of the scrotum due to traumatic pneumothorax is not an urgent condition and assessment should be supportive with intervention directed at the etiology.
RDL Kalıcı Kaydıİncele - ArticleAçık Erişim2013Effectiveness of Intragastric Balloon Treatment for Obese Patients: Retrospective Clinical Trial
Peker, Kemal; Isik, Arda; Çimen, Orhan; Demirtas, Levent; Kuyrukluyildiz, Ufuk
Objective: Obesity is a serious and chronic disease with genetic and environmental interference. Several treatment modalities exist such as medical treatment, surgical treatment, endoscopic interventions. Methods: Thirteen patients' data were evaluated retrospectively at the Erzincan University Medical Faculty Hospital Endoscopy Unit. Intragastric balloons were performed between 2012 January-2013 December. When patients gain the desired weight, approximately 8 to 12 months later; the balloons were removed. Results: The mean duration of gastric balloons in patients was 10.0 +/- 1.22 months. It was determined that the mean weight loss within the prescribed time was 25.1 +/- 5.5 kg. There is a statistically significant difference among the values when comparing the values before and after gastric balloon (p=0.001) Conclusion: Intragastric balloon replacement is a safe and effective procedure for weight reduction. The intragastric balloon can play a role for the temporary weight reduction of morbidly obese patients in diet supporting, as well as in the preoperative treatment of patient candidates for bariatric surgery or other surgical procedures in order to decrease morbidity and mortality.
RDL Kalıcı Kaydıİncele - ArticleAçık Erişim2013Comparison of vessel sealing systems with conventional
Peker, Kemal; Inal, Abdullah; Güllü, Huriye; Gül, Düriye; Şahin, Murat; Ozcan, Ayca Dumanli; Kiliç, Kemal
Background: Haemorrhoids are cushions of submucosal vascular tissue located in the anal canal starting just distal to the dentate line. Haemorrhoidal disease is a common anorectal disorder which has symptoms of bleeding, prolapse, pain, thrombosis, mucus discharge, and pruritus. Haemorrhoidectomy is one of most frequently performed anorectal operation worldwide. Objectives: The aim of this study was to compare the effectiveness of the LigaSure tissue sealing device, Harmonic Scalpel and conventional MM open haemorrhoidectomy. Materials and Methods: Sixty-nine patients with newly diagnosed symptomatic grade three or grade four haemorrhoidal disease, from July 2011 to December 2011 were recruited for the study. Patients were prospectively randomized to LigaSure, Harmonic Scalpel and conventional haemorrhoidectomy. Patients were evaluated on the basis of the mean operative time, postoperative pain, day of discharge, early and late complications. Results: Each group has twenty-three patients. Ten (14.5 %) were female and fifty-nine (85.5 %) were male. Mean age were 44.5 ± 10.8 for LigaSure group, 39.5±14.4 for Harmonic Scalpel group and 39.8 ± 13.6 for conventional haemorrhoidectomy group. Mean operative time was 12.6 ± 2.9 for LigaSure group, 12.6 ± 2.5 for Harmonic Scalpel group and 22.3 ± 4.5 for conventional haemorrhoidectomy group. Postoperative pain and required analgesic dose were significantly lower for conventional haemorrhoidectomy. Wound healing was also more rapid in conventional haemorrhoidectomy than both LigaSure and Harmonic Scalpel. Conclusions: Lateral heat dissipation of energy based cautery such as Harmonel Scalpel and LigaSure is considerably high when compared with conventional methods. More thermal damage which is generated on tissue seems to be the reason for increased degree of postoperative pain and delay in wound healing.
RDL Kalıcı Kaydıİncele - ArticleAçık Erişim2013Prevention of intraabdominal adhesions by local and systemic administration of immunosuppressive drugs
Peker, Kemal; Inal, Abdullah; Sayar, Ilyas; Sahin, Murat; Gullu, Huriye; Inal, Duriye Gul; Isik, Arda
Background: Intraperitoneal adhesion formation is a serious postsurgical issue. Adhesions develop after damage to the peritoneum by surgery, irradiation, infection or trauma. Objectives: Using a rat model, we compared the effectiveness of systemic and intraperitoneally administered common immunosuppressive drugs for prevention of postoperative intraperitoneal adhesions. Materials and Methods: Peritoneal adhesions were induced in 98 female Wistar-Albino rats by cecal abrasion and peritoneal excision. Rats were randomly separated into seven groups, each containing fourteen rats, and the standard experimental model was applied to all of rats. 14 days later, rats were euthanized, intraperitoneal adhesions were scored and tissues were examined histologically using hematoxylin/eosin and Masson's trichrome staining. Results: Throughout the investigation, no animal died during or after surgery. In all of experimental groups, decrease in fibrosis was statistically significant. Decrease in fibrosis was most prominently in intraperitoneal tacrolimus group (P = 0.000), and decrease was least in intraperitoneal cyclosporine group (P = 0.022). Vascular proliferation was significantly decreased in all experimental groups (P < 0.05) except for systemic tacrolimus group (P = 0.139). Most prominent reduction in vascular proliferation was in intraperitoneal tacrolimus group (P = 0.000). Conclusions: Administration of immunosuppressive drugs is effective for prevention of intraperitoneal adhesions.
RDL Kalıcı Kaydıİncele - ArticleAçık Erişim2013Primary uterine hydatid cyst: a case report.
Peker, Kemal; Uluǧ, Paşa; Nayki, Ümit Aslan; Nayki, Cenk; Sayar, Ilyas; Karakeçili, Faruk; Yildirim, Yusuf
Echinococcosis, which is caused by echinococcus granulosus, is also known as cystic hydatid disease, unilocular echinococcosis or cystic echinococcosis. Cystic echinococcosis is an alarming public health problem in some countries. Although the liver and lung are the organs involved most commonly by the disease, it may appear rarely in other tissues as a primary disease. Here, we present a 66-year-old patient who is invoved in farm work work. A Uterine multiseptate hydatid cyst was found on radiological investigations and the patient underwent surgery. A total hysterectomy was carried out. There were no postoperative complications.
RDL Kalıcı Kaydıİncele - ArticleYalnız künye2013A comparison of the efficacy of dimethyl sulfoxide (DMSO) and synovial fluid in the prevention of peritoneal adhesions: Experimental rabbit model; [Peritoneal adezyonların önlenmesinde dimetil sülfoksit (DMSO) ve synovial sıvı etkinliǧinin karşılaştırılması: Deneysel tavşan modeli]
Kiliç, Kemal; Kiliç, Nergiz; Kiliç, Engin; Yayla, Sadik; Ermutlu, Celal Şahin; Özaydin, Isa; Peker, Kemal; Daǧ, Serpil
The purpose of this study was to compare the efficacy of dimethyl sulfoxide and synovial fluid (SF) in the prevention of peritoneal adhesions that might develop in connection with the use of mersilen mesh in a ventral hernia model created experimentally in rabbits. The forty rabbits used in the study were divided into four groups of ten. The operation was conducted under intrathecal anesthesia induced with ketamine HCl (30 mg/kg intrathecal) following xylazin HCl (5 mg/kg intramuscular) sedation. A median skin incision was made in rabbits placed on the operating table in the supine position. Then, a defect 2 cm in diameter was created on the linea alba. The defect was repaired with mersilen mesh which had been previously prepared in the shape of a disk. Until the 7th day after the operation, group I was given 10 ml saline (S) and 1.5 g/kg DMSO, group II was given 7 ml saline, 3 ml synovial fluid (SF) and 1.5 g/kg DMSO, group III was given 7 ml saline and 3 ml SF while group IV (control: C) was given only 10 ml saline. All of these were administered intraperitoneally. At the end of the 10th day, the presence and extent of peritoneal adhesion was checked using Jenkins' (1983) visual adhesion scale by performing a relaparotomy. All of the data obtained from the study was analyzed statistically using the Minitab-16 package program. Tissue samples from the region where the graft was performed were evaluated under a light microscope by staining them with the Hematoxilen-Eosin (HE) and Crossman triple stain method. The results of the adhesion scale were evaluated nonparametrically and statistical calculations were performed with the Kruskal-Wallis test. No statistical difference was found between the groups (P>0.05). The results of histopathological examination revealed that the tissue which covered the graft in all of the groups was fibrous tissue. However, it was determined that the fibrosis was weaker in the DMSO group than it was in the SF-DMSO, SF and S groups. In the end, it was concluded that synovial fluid is effective in preventing postoperative peritoneal adhesions in rabbits in light of both relaparotomic, macroscopic findings and histopathological findings.
RDL Kalıcı Kaydıİncele - ArticleAçık Erişim2013Relationship between β -catenin expression and prognostic parameters of colorectal carcinomas; [β-catenin ekspresyonunun kolorektal karsinomlarda prognostik parametreler ile ilişkisi]
Peker, Kemal; Başoǧlu, Mahmut; Gürsan, Nesrin
Objective: Colorectal carcinomas are the most frequent tumors of the gastrointestinal tract. β-catenin, which is related to cadherins, is a cytoplasmic protein responsible for intercellular adhesion. It is also an important component in the Wnt signal pathway. Recent studies have shown structural alterations in the APC gene and axin in patients with colorectal carcinoma, along with β-catenin. We aimed to compare β-catenin expression, which is a prognostic factor itself, with other prognostic parameters. Material and Method: A total of 70 patients who had surgical intervention for colorectal malignancies between January 1994 and December 2003 were included in the study. Fifty-nine of the patients (84.3%) were male, 11 of the patients (15.7%) were female; their ages varied between 24 and 82 (mean 60.3 ±15.2) years. Paraf in blocks were immunohistochemically stained for β-catenin. The number of stained cell nuclei was assessed according to the stage of disease using the TNM classification, histological grade, lymphatic invasion, vascular invasion and tumor's local invasion. Results: When groups constituted according to tumor histologic grade were compared for prognostic parameters in terms of stain density for β-catenin and number of stained cell nuclei, stain density was mild (+) and the number of stained nuclei was smaller in well-differentiated groups while stain density was strong (+++) and the number of stained nuclei was higher in poorly differentiated groups. There was a relation between β-catenin expression and dif erentiation grade, lymph node metastasis, stage and tumor size but not with vascular invasion. Conclusion: These data indicate that β- catenin, with functions in cell homeostasis and relations with the APC gene, has a substantial role in colorectal carcinogenesis.
RDL Kalıcı Kaydıİncele - ArticleAçık Erişim2012Laparoscopic cholecystectomy in patients with situs inversus totalis: Literature review of two patients
Demiryilmaz, Ismail; Yilmaz, Ismayil; Albayrak, Yavuz; Peker, Kemal; Sahin, Atalay; Sekban, Nurdan
Situs inversus totalis is a rare condition, which presents difficulties in diagnosis and treatment of gallstones due to the reversal location of abdominal organs. In this article we present 2 cases of women in age of 51 and 55 years with situs inversus totalis and gallstones. There are described the clinical and imaging features, also the laparoscopic surgery with the difficulties encountered by right handed surgeon. In patients with situs inversus totalis, laparoscopic surgery may be performed safely by a surgeon with experience.
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