Recommendations of the International Society of Geriatric Oncology on skin cancer management in older patients

ArticleAçık Erişim

Özet

Introduction: Non-melanoma skin cancer (NMSC) is becoming ever more prevalent among older adults. However, older adults with NMSC are often underrepresented in clinical trials and guidelines on effective management is still unclear. The International Society of Geriatric Oncology (SIOG) created a multi-disciplinary task force to explore the potential in developing practical guidelines for the treatment of older patients with basal cell carcinoma (BCC) and skin (cutaneous) squamous cell carcinoma (cSCC). Materials and Methods: A systematic literature search to identify relevant and up-to-date literature on treatment of NMSC in older adults was conducted on various databases including MEDLINE, Embase, CINAHL, Cochrane, and PubMed. The resulting papers were discussed by an expert panel, leading to a consensus recommendation. Results: A total of 154 articles were identified for the expert panel to utilise in generating consensus recommendations. A major focus on geriatric assessment and management options including surgery, radiotherapy, systemic therapy, clinical monitoring, and medical/medicophysical therapy were reviewed for recommendations. Discussion: Patient age should not be the sole deciding factor in the management of patients with NMSC. Assessment from a multidisciplinary team (MDT) is crucial, and the decision-making process should consider the patient's lifestyle, needs, and expectations. A comprehensive geriatric assessment should also be considered. Patients should feel empowered to advocate for themselves and have their views considered a part of the MDT discussion. © 2023 Elsevier Ltd

Anahtar Kelimeler

RDL Kalıcı Bağlantı (PID)
https://rdlopen.rawdatalibrary.net/r/ebyu/12383Resmi atıflarda kullanılan kalıcı adres
DOI
https://doi.org/10.1016/j.jgo.2023.101502Yayıncı resmi DOI adresi
Tam Kayıt
AlanDeğerDil
dc.contributor.authorRembielak, Agata
dc.contributor.authorYau, Thomas
dc.contributor.authorAkagunduz, Baran
dc.contributor.authorAspeslagh, Sandrine
dc.contributor.authorColloca, Giuseppe
dc.contributor.authorConway, Aoife
dc.contributor.authorDanwata, Falalu
dc.contributor.authordel Marmol, Veronique
dc.contributor.authorO'Shea, Chuck
dc.contributor.authorVerhaert, Marthe
dc.contributor.authorZic, Rado
dc.contributor.authorLivesey, Dan
dc.date.accessioned2026-10-18T20:27:17.617415789Z
dc.date.available2026-10-18T20:27:17.617415789Z
dc.date.issued2023
dc.description.abstractIntroduction: Non-melanoma skin cancer (NMSC) is becoming ever more prevalent among older adults. However, older adults with NMSC are often underrepresented in clinical trials and guidelines on effective management is still unclear. The International Society of Geriatric Oncology (SIOG) created a multi-disciplinary task force to explore the potential in developing practical guidelines for the treatment of older patients with basal cell carcinoma (BCC) and skin (cutaneous) squamous cell carcinoma (cSCC). Materials and Methods: A systematic literature search to identify relevant and up-to-date literature on treatment of NMSC in older adults was conducted on various databases including MEDLINE, Embase, CINAHL, Cochrane, and PubMed. The resulting papers were discussed by an expert panel, leading to a consensus recommendation. Results: A total of 154 articles were identified for the expert panel to utilise in generating consensus recommendations. A major focus on geriatric assessment and management options including surgery, radiotherapy, systemic therapy, clinical monitoring, and medical/medicophysical therapy were reviewed for recommendations. Discussion: Patient age should not be the sole deciding factor in the management of patients with NMSC. Assessment from a multidisciplinary team (MDT) is crucial, and the decision-making process should consider the patient's lifestyle, needs, and expectations. A comprehensive geriatric assessment should also be considered. Patients should feel empowered to advocate for themselves and have their views considered a part of the MDT discussion. © 2023 Elsevier Ltd
dc.description.sponsorshipThis activity is supported by an independent medical education grant from Regeneron Pharmaceuticals, Inc. and Sanofi Genzyme, and Xstrahl .
dc.identifier.doi10.1016/j.jgo.2023.101502
dc.identifier.issn1879-4068
dc.identifier.issue4
dc.identifier.pmid37080793
dc.identifier.scopus2-s2.0-85152909846
dc.identifier.startpage101502
dc.identifier.urihttps://rdlopen.rawdatalibrary.net/r/ebyu/12383
dc.identifier.volume14
dc.language.isoen
dc.publisherElsevier Ltd
dc.relation.ispartofJournal of Geriatric Oncology
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBasal cell carcinoma
dc.subjectCancer treatment
dc.subjectCutaneous squamous cell carcinoma
dc.subjectGeriatric assessment
dc.subjectOlder patients
dc.subjectSkin cancer
dc.subjectAged
dc.subjectCarcinoma, Basal Cell
dc.subjectCarcinoma, Squamous Cell
dc.subjectHumans
dc.subjectRadiation Oncology
dc.subjectSkin Neoplasms
dc.subjectcemiplimab
dc.subjectfluorouracil
dc.subjectimiquimod
dc.subjectage
dc.subjectArticle
dc.subjectbrachytherapy
dc.subjectcancer chemotherapy
dc.subjectcancer immunotherapy
dc.subjectcancer therapy
dc.subjectclinical monitoring
dc.subjectcryotherapy
dc.subjectexternal beam radiotherapy
dc.subjectfollow up
dc.subjecthuman
dc.subjectMohs micrographic surgery
dc.subjectnursing care
dc.subjectpalliative therapy
dc.subjectpatient advocacy
dc.titleRecommendations of the International Society of Geriatric Oncology on skin cancer management in older patients
dc.typeArticle
dspace.entity.typePublication
rdl.citation.scopus19
rdl.departmentYoung SIOG Member, Department of Medical Oncology, Erzincan Binali Yıldrıım University Medical School, Erzincan, Turkey.
rdl.source.indexSCOPUS
rdl.source.indexPUBMED