The comparative effects of genetically modified maize and conventional maize on rats; [Genetik olarak deǧiştirilmiş mısır ve konvensiyonel mısırın sıçanlardaki etkilerinin karşılaştırılması]

ArticleAçık Erişim

Özet

Aim: Genetically modified crops have a potential to solve many of the world's nutrition problems. On the other hand, the impact of these novel crops on environmental, animal and human health should be tested and their risk assessment is required. In this study, the aim of this study was to investigate the positive or possible negative effects of genetically modified maize on offspring rats which were between the start of dry food feeding and the time interval until they reached puberty. Material and Method: Thirty Wistar albino rats were used in this study. The rats were fed with transgenic Bacillus thuringiensis maize and conventional maize during 40 days. After the experimental period, the length, height and weight of organs and serum chemistry and hematology values were measured. Results: The length, height and weight of liver, spleen, lung and kidneys in Bacillus thuringiensis maize group of rats were different from those in control and conventional groups. When mean values of serum chemistry and hematology parameters, which were glucose, urea, total protein, cholesterol, triglyceride, very low-density lipoprotein, low-density lipoprotein, calcium, phosphorus, sodium, potassium, chlorine were examined, some obvious differences were found between the rats fed with transgenic maize and its conventional counterpart and control groups. Discussion: The results of this study showed that Bacillus thuringiensis maize may not only have an effect on the length, height and weight of organs of the maturing term of rats but also lead to alterations in serum chemistry and hematology values.

Anahtar Kelimeler

RDL Kalıcı Bağlantı (PID)
https://rdlopen.rawdatalibrary.net/r/ebyu/15522Resmi atıflarda kullanılan kalıcı adres
DOI
https://doi.org/10.4328/jcam.983Yayıncı resmi DOI adresi
Tam Kayıt
AlanDeğerDil
dc.contributor.authorKiliçgün, Hasan
dc.contributor.authorGürsul, Cebrail
dc.contributor.authorSunar, Mukadder
dc.contributor.authorGökşen, Gülden
dc.date.accessioned2026-10-18T20:30:21.941551455Z
dc.date.available2026-10-18T20:30:21.941551455Z
dc.date.issued2013
dc.description.abstractAim: Genetically modified crops have a potential to solve many of the world's nutrition problems. On the other hand, the impact of these novel crops on environmental, animal and human health should be tested and their risk assessment is required. In this study, the aim of this study was to investigate the positive or possible negative effects of genetically modified maize on offspring rats which were between the start of dry food feeding and the time interval until they reached puberty. Material and Method: Thirty Wistar albino rats were used in this study. The rats were fed with transgenic Bacillus thuringiensis maize and conventional maize during 40 days. After the experimental period, the length, height and weight of organs and serum chemistry and hematology values were measured. Results: The length, height and weight of liver, spleen, lung and kidneys in Bacillus thuringiensis maize group of rats were different from those in control and conventional groups. When mean values of serum chemistry and hematology parameters, which were glucose, urea, total protein, cholesterol, triglyceride, very low-density lipoprotein, low-density lipoprotein, calcium, phosphorus, sodium, potassium, chlorine were examined, some obvious differences were found between the rats fed with transgenic maize and its conventional counterpart and control groups. Discussion: The results of this study showed that Bacillus thuringiensis maize may not only have an effect on the length, height and weight of organs of the maturing term of rats but also lead to alterations in serum chemistry and hematology values.
dc.identifier.doi10.4328/jcam.983
dc.identifier.eissn1309-2014
dc.identifier.endpage139
dc.identifier.issn1309-0720
dc.identifier.issue2
dc.identifier.scopus2-s2.0-84867089333
dc.identifier.startpage136
dc.identifier.urihttps://rdlopen.rawdatalibrary.net/r/ebyu/15522
dc.identifier.volume4
dc.identifier.wosWOS:000215548100017
dc.language.isoen
dc.publisherDerman Medical Publishing
dc.relation.ispartofJournal of Clinical and Analytical Medicine
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBt maize
dc.subjectGenetically modified organisms
dc.subjectGMO
dc.subjectRat
dc.subjectcalcium
dc.subjectchloride
dc.subjectcholesterol
dc.subjectglucose
dc.subjectlow density lipoprotein
dc.subjectphosphorus
dc.subjectpotassium
dc.subjectsodium
dc.subjecttriacylglycerol
dc.subjecturea
dc.subjectvery low density lipoprotein
dc.subjectanimal experiment
dc.subjectanimal tissue
dc.subjectarticle
dc.subjectBacillus thuringiensis
dc.subjectblood analysis
dc.subjectbody height
dc.subjectcomparative study
dc.subjectcontrolled study
dc.subjectfood intake
dc.subjectfood quality
dc.subjectfood safety
dc.subjectgenetic difference
dc.subjectgenetic similarity
dc.subjectmaize
dc.subjectmale
dc.titleThe comparative effects of genetically modified maize and conventional maize on rats; [Genetik olarak deǧiştirilmiş mısır ve konvensiyonel mısırın sıçanlardaki etkilerinin karşılaştırılması]
dc.typeArticle
dspace.entity.typePublication
rdl.citation.scopus5
rdl.citation.wos5
rdl.oa.statusgold
rdl.source.indexSCOPUS
rdl.source.indexWOS
rdl.wos.indexEmerging Sources Citation Index (ESCI)