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A Flow-Injection Potentiometric System for Selective and Sensitive Determination of Serum Lithium Level

ArticleAçık Erişim

Özet

A potentiometric flow injection system was adopted by using a Li+-selective electrode with improved selectivity for sensitive and selective determination of Li+ in human serum spiked samples. For the optimization of the offered flow injection system, multivariate method was utilized. Potentiometric characteristics of the system were investigated (linear range: 5.0×10-5-1.0×10-1molL-1, slope: 56.93mV per decade, detection limit: 3.4×10-5molL-1, sampling-rate: 40 injections per hour). The detection of Li+ in real serum samples was achieved. The obtained results for the spiked serum samples were in good agreement with IC results at 95% confidence level. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Anahtar Kelimeler

Experimental designFlow injection analysisLithium determinationMultivariate optimizationSerum analysisBody fluidsMultivariant analysisPotentiometers (electric measuring instruments)Flow injectionFlow-injection systemLi +Potentiometric flowsPotentiometricsSerum samplesLithium
RDL Kalıcı Bağlantı (PID)
https://rdlopen.rawdatalibrary.net/r/ebyu/15861Resmi atıflarda kullanılan kalıcı adres
DOI
https://doi.org/10.1002/elan.201200466Yayıncı resmi DOI adresi
Tam Kayıt
AlanDeğerDil
dc.contributor.authorColdur, Fatih
dc.contributor.authorAndac, Muberra
dc.date.accessioned2026-10-18T20:30:42.577318294Z
dc.date.available2026-10-18T20:30:42.577318294Z
dc.date.issued2013
dc.description.abstractA potentiometric flow injection system was adopted by using a Li+-selective electrode with improved selectivity for sensitive and selective determination of Li+ in human serum spiked samples. For the optimization of the offered flow injection system, multivariate method was utilized. Potentiometric characteristics of the system were investigated (linear range: 5.0×10-5-1.0×10-1molL-1, slope: 56.93mV per decade, detection limit: 3.4×10-5molL-1, sampling-rate: 40 injections per hour). The detection of Li+ in real serum samples was achieved. The obtained results for the spiked serum samples were in good agreement with IC results at 95% confidence level. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
dc.description.sponsorshipThe authors gratefully acknowledge the financial support from The Scientific and Technological Research Council of Turkey (TUBITAK) (Project No: 107T-356) and Ondokuz Mayis University (Project No: OMU-BAP F-448).
dc.identifier.doi10.1002/elan.201200466
dc.identifier.eissn1521-4109
dc.identifier.endpage740
dc.identifier.issn1040-0397
dc.identifier.issue3
dc.identifier.scopus2-s2.0-84874961982
dc.identifier.startpage732
dc.identifier.urihttps://rdlopen.rawdatalibrary.net/r/ebyu/15861
dc.identifier.volume25
dc.identifier.wosWOS:000316213900021
dc.language.isoen
dc.publisherWiley-VCH Verlag
dc.relation.ispartofElectroanalysis
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectExperimental design
dc.subjectFlow injection analysis
dc.subjectLithium determination
dc.subjectMultivariate optimization
dc.subjectSerum analysis
dc.subjectBody fluids
dc.subjectMultivariant analysis
dc.subjectPotentiometers (electric measuring instruments)
dc.subjectFlow injection
dc.subjectFlow-injection system
dc.subjectLi +
dc.subjectPotentiometric flows
dc.subjectPotentiometrics
dc.subjectSerum samples
dc.subjectLithium
dc.titleA Flow-Injection Potentiometric System for Selective and Sensitive Determination of Serum Lithium Level
dc.typeArticle
dspace.entity.typePublication
rdl.citation.scopus23
rdl.citation.wos22
rdl.source.indexSCOPUS
rdl.source.indexWOS
rdl.wos.indexScience Citation Index Expanded (SCI-EXPANDED)