Araştırmacılar(9)

• Bilgin, Yasin
• Cimen, Erdem Yakup
• Eden, Arif Onur
• Isik, Bahar
• Kantar, Yusuf
• Kilic, Mert
• Sari, Fatih Mehmet
• Tanrıverdi, Orhan
• Yurttutan, Abdullah Emre

• ArticleYayıncıda açık erişim2026/r/ebyu/18312
  Evaluation of Paramedic Pre-hospital's Analgesic Management of Trauma Patients

  Kantar, Y.; Hayme, S.

  Background:Although analgesic management is a critical priority in the guidelines for trauma patients, paramedics' prehospital administration practices vary.Objectives:This study evaluated the paramedics' practices regarding prehospital analgesia administration in trauma patients.Methods:The study was conducted in two phases. In the first phase, the records of patients 18 years and above who were brought to our hospital via ambulance were retrospectively reviewed. A total of 506 patients with trauma were included in this phase of the study. In the second phase, paramedics' practices regarding pre-hospital analgesic administration to trauma patients, such as drugs, and frequency. Data were analyzed using descriptive statistics, and are presented as mean +/- standard deviation for numerical variables and as frequency and percentage for nominal variables. Nominal variables were evaluated using the Pearson Chi-Square test.Results:According to data collected retrospectively in the first phase of the study, prehospital analgesia was administered to only 1% of the 506 patients. In the second phase of the study, when asked about the reasons for not administering prehospital analgesia, it was found that 77.5% of paramedics believed that doing so would interfere with the hospital physician's examination.Conclusion:High rates of interventions such as spinal board immobilization, cervical collar application, and appropriate splinting or dressing have been observed in trauma patients. Paramedics were also found to be quite successful in establishing intravenous access. However, the rates of fluid administration and analgesia were considerably lower compared to the literature.

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• ArticleYayıncıda açık erişim2026/r/ebyu/18341
  A Rare Cause of Respiratory Failure in an Alzheimer's Patient: Esophagual ForeignBody

  Kantar, Yusuf

  Foreign body impaction in the esophagus is a common emergency, particularly among children; however, unusual presentations in geriatric patients are rarely encountered. The clinical manifestation may vary depending on the type and location of the foreign body and the patient's underlying condition. We report the case of a 79-year-old bedridden male patient with Alzheimer's disease who presented to the emergency department with shortness of breath and audible wheezing. Initial evaluation and imaging studies revealed no acute pulmonary pathology. A lateral neck X-ray demonstrated an image consistent with a foreign body at the cervical level, which was later confirmed by computed tomography to extend along the esophagus. Under sedation with fentanyl and ketamine, the foreign body-a sock-was successfully removed using a laryngoscope and long forceps. The patient recovered uneventfully and was discharged after clinical stabilization. This case is remarkable due to the atypical presentation and the unusual nature of the ingested object. While most esophageal foreign bodies in adults are accidental or intentional, this case resulted from unconscious behavior related to Alzheimer's disease. Emergency physicians should maintain a high index of suspicion when evaluating elderly or cognitively impaired patients presenting with atypical respiratory symptoms, as early recognition and prompt intervention can be lifesaving.

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• ArticleAçık Erişim2026/r/ebyu/19226
  Clinical Characteristics of Geriatric Patients Admitted to the Emergency Department and Evaluation According to Age Groups

  Bilgin, Yasin; Kantar, Yusuf; Tanrıverdi, Orhan; Sari, Fatih Mehmet; Çimen, Erdem Yakup; Yurttutan, Abdullah Emre

  Objective: To evaluate the demographic and clinical characteristics, reasons for admission, triage distribution, consultation requests, and hospitalization rates of geriatric patients presenting to a tertiary emergency department, and to examine the associations between age groups and emergency department utilization patterns and outcomes. Materials and Methods: This retrospective and descriptive study was conducted among patients aged 65 years and older who presented to the emergency department of Mengücek Gazi Training and Research Hospital between July 1, 2024, and June 30, 2025. Data on demographic characteristics, triage categories, reasons for admission, consultation requests, hospitalization status, emergency department outcomes, and repeat visits were obtained from the hospital information management system. The data were analyzed using descriptive statistical methods. Results: A total of 18,269 geriatric patients were included in the study. The mean age was 74.0 ± 7.2 years, and 54.5% of the patients were female. The highest proportion of admissions was observed in the 65-74 age group. Hospitalization occurred in 11.4% of cases. As age increased, ambulance admissions, repeat emergency department visits, and hospitalization rates increased significantly (P < 0.05). The most common reasons for admission were musculoskeletal, respiratory, and cardiovascular diseases. Conclusion: This study demonstrates that geriatric patients presenting to the emergency department exhibit distinct clinical and utilization characteristics by age group. The findings indicate that patients in older age groups require more complex clinical evaluation and tailored care during management in the emergency department.

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• ArticleAçık Erişim2026/r/ebyu/19038
  Investigation of Sensitivity and Specificity of Biochemical Markers for Cardiac Contusion due to Blunt Chest Trauma

  Elma, Bekir; Bilgin, Yasin; Sari, Fatih Mehmet; Emet, Mucahit; Öz, Funda

  Objective: There remains a significant need for precise biomarkers to diagnose cardiac contusion. The objective of this study is to examine the diagnostic significance of cardiac myosin-binding protein-C (cMyBP-C) in thoracic injuries, including cardiac contusion. Methods: The inclusion criteria were patients who consented to take part, were over 18 years of age, had sustained severe blunt chest injuries, were admitted within 24 hours post-injury, had their blood samples taken within the first 2 hours of admission, and had at least one of the following injuries: sternal, rib, or left scapular fractures; hemothorax, pneumothorax, pulmonary contusion, traumatic asphyxia, or pneumomediastinum. Troponin I levels ≥ 0.04 ng/mL, measured within 2 hours of admission, are considered the gold standard for diagnosing cardiac contusion. Serum troponin-I concentrations were assessed using an immunochemical technique. Serum cMyBP-C concentrations were measured using an enzyme-linked immunosorbent assay. Results: Participants included 85 patients, with 59 men (69.4%) and a mean age of 48.6 ± 20.8 years (range: 18-84 years). Among them, 18 individuals (21.2%) experienced cardiac contusion. No significant difference was observed in cMyBP-C levels between the cardiac contusion group and the other group (17.7 ± 18.6 vs. 14 ± 15.3, P = 0.328). Receiver operating characteristic analysis revealed that the discriminative performance of cMyBP-C in distinguishing contusion was not statistically significant. In this analysis, the area under the curve for cMyBP-C was 0.575 ± 0.077 (95% confidence interval, 0.425-0.726; P = 0.328), indicating poor discriminative ability and a lack of statistically significant diagnostic value for contusion. Conclusion: While cMyBP-C holds theoretical promise as a cardiomyocyte-specific biomarker, our findings suggest that its current diagnostic performance may be limited in the context of blunt cardiac contusion. Further studies with larger cohorts and refined detection methods are warranted to clarify its clinical utility.

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• ArticleAçık Erişim2026/r/ebyu/19037
  The Relationship Between Allergic Reactions and Serum Erythropoietin Levels: A New Biomarker Candidate in Allergic Reactions

  Bilgin, Yasin; Sari, Fatih Mehmet; Emet, Mucahit; Sari, Haticetul Kubra

  Objective: This study aimed to compare serum erythropoietin (EPO) levels in patients admitted to the emergency department with allergic reactions who were clinically diagnosed with urticaria, angioedema, or anaphylaxis, and to evaluate the diagnostic value of EPO as a potential biomarker. Methods: The study was conducted prospectively in the Emergency Department of Atatürk University between 2013 and 2016. A total of 156 patients diagnosed with urticaria, angioedema, or anaphylaxis were included. Serum EPO levels from blood samples taken at admission were analyzed using the enzyme-linked immunosorbent assay method. Relationships between vital signs, clinical symptoms, and EPO levels were statistically evaluated. Results: No significant difference in serum EPO levels was observed among the urticaria (41.7%), angioedema (35.9%), and anaphylaxis (24.4%) groups (P = 0.799). However, patients with uvular edema had significantly higher EPO levels (6.5 ± 1.6 vs. 6.0 ± 1.7 mIU/mL; P = 0.027). In the anaphylaxis group, oxygen saturation and blood pressure were significantly lower, whereas pulse rate and respiratory rate were significantly higher. Conclusion: EPO levels alone are not sufficient for differential diagnosis of acute allergic reactions. However, when assessed alongside specific symptoms, such as uvular edema, EPO may reflect the severity of the inflammatory response and serve as a potential biomarker. Multicenter studies including tissue-level analyses are needed to better understand the role of EPO in allergic inflammation.

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• ArticleAçık Erişim2026/r/ebyu/18896
  Comparison of Intern Doctors and ChatGPT in Emergency Cases Assessment

  Kantar, Yusuf; Imamoglu, Melih; Bülbül, Emre; Hayme, Serhat; Eden, Arif Onur; Bilgin, Yasin; Sari, Fatih Mehmet

  Objective: Accurate and timely diagnosis in emergency departments is crucial due to the high patient volume and time-sensitive nature of care. Intern doctors, who are nearing the completion of medical school, frequently work in emergency departments in many countries. However, after graduation, physicians are often expected to assume critical patient care responsibilities despite limited experience. Artificial intelligence models can quickly analyze patient data and generate diagnoses, thus assisting inexperienced physicians in enhancing diagnostic accuracy. This study aims to evaluate the diagnostic performance of ChatGPT-4 in emergency department case scenarios and compare its accuracy with that of intern doctors. Materials and Methods: This study involved intern doctors participating in the internship program during the 2024-2025 academic year. A total of 36 case-based questions, categorized by difficulty level, were administered to 155 interns and subsequently presented to artificial intelligence. Descriptive statistics were used to summarize the data, and a one-sample t-test was conducted to compare the diagnostic accuracy between intern doctors and ChatGPT. Statistical significance was set at p<0.05. Results: Intern doctors achieved an overall correct response rate of 58.3%, while ChatGPT achieved a rate of 97.2%. A statistically significant, moderate negative correlation was found between question difficulty and interns' performance (r=-0.684; p<0.001), indicating decreased accuracy as question difficulty increased. ChatGPT consistently demonstrated significantly higher performance across all difficulty levels. Conclusion: ChatGPT-4 may serve as a valuable diagnostic support tool in emergency departments, particularly for newly graduated physicians with limited clinical experience.

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• Book ChapterYalnız künye2026/r/ebyu/10944
  Hand Hygiene Rules in Emergency Departments

  Kantar, Yusuf; Imamoglu, Melih

  This chapter addresses the significance of maintaining hand hygiene in EDs and highlights critical considerations in its implementation. Hand hygiene is one of the most fundamental methods for preventing healthcare-associated infections (HAIs) and, despite being discovered centuries ago, continues to retain its pivotal importance. Numerous methods are available to ensure effective hand hygiene; even basic handwashing with soap and water can prevent a significant proportion of HAIs. The “Five Moments for Hand Hygiene” outlined by the World Health Organization (WHO) has become a standard protocol for all hospital units. However, in EDs, which operate 24/7 and are often overcrowded, maintaining proper hand hygiene is even more crucial for preventing nosocomial infections. The broad clinical spectrum of patients admitted to EDs creates a high-risk environment where diverse pathogens coexist. Additionally, family members and visitors can also serve as potential sources of infection. Given the high patient turnover and the frequency of invasive procedures, neglecting hand hygiene is likely to result in serious cross-contamination issues.

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• ArticleYayıncıda açık erişim2026/r/ebyu/10820
  Liraglutide Attenuates Multiorgan Oxidative, Astroglial, and Mitochondrial Stress Responses in Thioacetamide-Induced Hepatic Encephalopathy

  Bilgin, Yasin; Sari, Fatih Mehmet; Cicek, Betul; Kurt, Engin; Ozkaraca, Mustafa; Gungor, Ali; Kurt, Nezahat; Bilgin, Asli Ozbek

  Hepatic encephalopathy (HE) is a complex complication of liver failure involving oxidative stress, astroglial activation, mitochondrial dysfunction, and multiorgan disturbances along the gut–liver–brain axis. This study investigated the therapeutic effects of liraglutide (LIRA) in a thioacetamide (TAA)-induced rat model of HE. Thirty male Sprague–Dawley rats were assigned to control, TAA, and TAA+LIRA 100, 200, or 400 µg/kg groups. HE was induced with TAA (200 mg/kg, intraperitoneally) for three consecutive days, followed by subcutaneous LIRA treatment for 14 days. Serum biochemical parameters, tissue oxidative and inflammatory markers, histopathology, and Nrf2, MFN2, AKT1, mTOR, GFAP, and VEGFA immunoreactivity were evaluated. TAA caused marked hepatic and cerebral structural injury, increased serum and brain glutamine concentrations, disrupted redox homeostasis, elevated MPO activity, and increased cerebral GFAP and multiorgan VEGFA immunoreactivity. LIRA partially improved hepatic and cerebral histopathology, reduced glutamine disturbances, attenuated selected oxidative, nitrosative, and inflammatory alterations, and modulated Nrf2, MFN2, AKT1, mTOR, GFAP, and VEGFA immunoreactivity in a tissue- and dose-specific manner. The 200 µg/kg dose produced the most consistent overall improvement, whereas the 400 µg/kg dose was less favorable for several endpoints. LIRA may therefore alleviate multiorgan stress associated with experimental HE, although further studies are required to confirm functional and mechanistic relevance.

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• ArticleYayıncıda açık erişim2026/r/ebyu/10642
  Smartphone Screen Time, Sleep Quality, and Headache in Young Adults Presenting to the Emergency Department: A Case–Control Study

  Kantar, Yusuf; Aslan, Yusuf Ertuğrul; Eden, Arif Onur; Bilgin, Yasin; Tanrıverdi, Orhan; Yurttutan, Abdullah Emre; Çimen, Erdem Yakup; Sarı, Fatih Mehmet

  Background: Smartphone screen exposure has increased substantially among young adults and has been associated with headache and sleep disturbances. This study aimed to investigate the associations between smartphone screen time, headache severity, sleep duration, and sleep quality in young adults presenting to the emergency department with headache. Methods: This single-center case–control study was conducted in the emergency department of a tertiary university hospital between November 2025 and April 2026. A total of 300 participants aged 18–40 years were enrolled, including 150 patients with headache and 150 controls without headache. Daily smartphone screen time was obtained from the built-in smartphone records for the preceding completed seven-day period, headache severity was assessed using the 11-point Numeric Rating Scale, and sleep quality was evaluated using the validated Turkish version of the Single-Item Sleep Quality Scale. Results: Participants with headache had longer smartphone screen time (7.0 vs. 5.0 h/day; p < 0.001), shorter sleep duration (7.0 vs. 8.0 h/day; p = 0.005), and poorer sleep quality (5.0 vs. 7.0; p < 0.001) than controls. Screen time correlated with headache severity (ρ = 0.430, p < 0.001) and inversely with sleep quality after adjustment for study group (partial ρ = −0.185, p = 0.001). Nonlinear multivariable modeling showed an association with headache presentation (p < 0.001); relative to 6 h/day, the aOR at 7 h/day was 8.83 (95% CI: 5.00–15.60), with a plateau at higher exposures. Conclusions: Longer device-recorded smartphone screen time was associated with headache presentation and severity in young adults. Participants with headache also reported poorer sleep quality and shorter sleep duration. These findings suggest relevant associations between smartphone exposure, sleep, and headache but do not establish causality or a clinical screen-time threshold. Prospective studies are warranted.

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• ArticleAçık Erişim2026/r/ebyu/10626
  Diagnostic performance of clinical symptom combinations for Crimean-Congo hemorrhagic fever in emergency department patients with reported arthropod bites, stings, or exposure

  Bilgin, Yasin; Sari, Fatih Mehmet; Sakal, Cemalettin; Cimen, Erdem Yakup; Tanrıverdi, Orhan; Yurttutan, Abdullah Emre; Binay, Umut Devrim

  Background: Crimean-Congo hemorrhagic fever (CCHF) is a potentially fatal tick-borne viral disease that remains an important public health problem in endemic regions. Early recognition of CCHF in emergency departments is challenging because initial clinical manifestations are often nonspecific. This study aimed to evaluate the demographic, clinical, and exposure-related characteristics of adult patients presenting to the emergency department after reported or clinically suspected arthropod bites, stings, or contact and to investigate clinical predictors associated with CCHF. Methods: This retrospective single-center study included adult patients presenting to the emergency department after reported or clinically suspected arthropod bites, stings, or contact between October 1, 2023, and October 1, 2024. A total of 526 patients were screened; 24 patients with incomplete data and 2 patients younger than 18 years were excluded. Demographic characteristics, clinical symptoms, and history of tick exposure were recorded. Clinical findings associated with CCHF were analyzed using univariable and multivariable statistical methods. The diagnostic performance of symptom combinations with tick exposure was evaluated using sensitivity, specificity, predictive values, likelihood ratios, odds ratios, and relative risks. Results: A total of 500 adult patients were included, and CCHF was confirmed in 38 patients (7.6%). The mean age was 49.48 ± 15.91 years, and 62.8% of the patients were male. Fever, headache, diffuse body aches, malaise, nausea/vomiting, diarrhea, abdominal pain, rash, ecchymosis, and history of tick exposure were significantly more frequent in CCHF-positive patients (all p < 0.05). CCHF positivity was significantly higher among patients with a history of tick exposure than among those without tick exposure (11.9% vs 3.8%; OR: 3.45, p = 0.001). Among symptom combinations evaluated with tick exposure, diffuse body aches showed the highest specificity (100.0%) and a very high positive likelihood ratio after continuity correction; however, these estimates should be interpreted cautiously because no CCHF-negative patient had this combination. In multivariable logistic regression analysis, malaise (adjusted OR: 117.29, 95% CI: 28.23–487.33, p < 0.001) and fever (adjusted OR: 6.41, 95% CI: 1.87–21.94, p = 0.003) were independently associated with CCHF. Conclusion: Simple clinical findings and symptom combinations may provide valuable early diagnostic clues for CCHF in endemic regions, even before laboratory confirmation. In particular, malaise and diffuse body aches in patients with a history of tick exposure showed high diagnostic performance and may contribute to early recognition and appropriate management of CCHF in emergency department settings.

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