EVALUATION OF THE RESULTS OF HEMATOLOGICAL PARAMETERS OF PATIENTS WITH GASTRIC CANCER

Objective: Gastric cancer is a major health concern which fourth leading cause of cancer death and fifth most common cancer. It has difficulties such as having a poor prognosis and diagnoses at an advanced stage. There are studies to find prognostic indicators that are easily and less invasively obtained in gastric cancer and hematological tests are one of them. In this study, we aimed to investigate the relation between hematological test and gastric cancer. Material and Methods: 48 patients diagnosed with gastric cancer and 45 healthy adults in the control group were examined prospectively. All participants' demographic data and laboratory results were obtained from the hospital database and recorded. Results: In the gastric cancer group compared to the healthy control group, while red blood cells (RBC), hemoglobin (HGB), hematocrit (HCT), mean cell hemoglobin concentration (MCHC), platelet distribution width (PDW), lymphocyte (LYM), eosinophil (EO) values were statistically lower, mean corpuscular hemoglobin (MCH), red cell distribution width-standard deviation, red cell distribution width-coefficient of variation (RDW-CV), nucleated red blood cells (NRBC), neutrophil lymphocyte ratio (NLR), platelet lymphocyte ratio (PLR) and monocyte lymphocyte ratio (MLR) values were observed statistically higher (p<0.05). RBC, HGB, HCT, LYM, RDW-SD, RDW-CV, NLR, PLR, and MLR exhibited considerably higher area under the curve (AUC) values in the receiver operating characteristic (ROC) analysis of these parameters (p<0.001). Conclusion: RBC, HGB, HCT, LYM, RDW-SD, RDW-CV, NLR, PLR, and MLR levels can be used as a supportive test to eliminate endoscopic delays in gastric cancer diagnosis.