Can systemic immune inflammation index measured in the first trimester predict later occurring isolated oligohydramnios?

The aim of our study is to determine whether the first trimester systemic immune inflammation index (SII) and other hematological markers can be useful as new markers of isolated oligohydramnios that may develop later. Two main groups were formed in this retrospective study. In the first group, 57 pregnant women with isolated oligohydramnios in their third trimester (between 28-40 weeks) were included. The control group consisted of 137 healthy pregnant women with a normal amniotic index (AFI) in the third trimester. First trimester and delivery hemogram values and newborn results of all pregnant women in both groups included in the study were noted for statistical comparison. Platelet (261.895+8.04), which is the hematological marker that best predicts IO in the first trimester, was found to be higher than the healthy group (244.390±4.79) (p=0.03). PLR was the best predictor of oligohydramnios in the third trimester. The PLR level was determined as 113,288, and the cut-off value was 64.91%, the upper limit was 95% CI, the specificity was 51.09%, the positive predictive value was 35.58%, and the negative predictive value was 77.78%. The platelet count in the first trimester and the progressive increase in the number of PLR in the third trimester are significantly related in the prediction of oligohydromnus. SII, NLR and PLR measured in the first trimester are useless in predicting isolated oligohydramnios that may develop in the future.