Sürdürülebilir Kalkınma Amaçları

• 4

Araştırmacılar(9)

• Bozatlı, Hande
• Kara, Gamze
• Karakaş, Batıkan
• Karataş, Onur
• Karataş, Zehra
• Kurtcu, Nagihan
• Özdemir, Şevki
• Tekgöz, Davut
• Yazıcı, Mustafa

• ArticleAçık Erişim2026/r/ebyu/19227
  Investigation of Nailfold Capillary Structures Using Digital Dermatoscopy in Rheumatological Diseases

  Ozdemir, Sevki; Sari, Haticetul Kubra

  Objective: Evaluating the microvascular structure in rheumatological diseases provides important information for understanding the pathogenesis and clinical management of these diseases. Nail capillaroscopy is a reliable method that allows non-invasive examination of these changes. This study aimed to evaluate nail capillary findings in rheumatological diseases using digital dermoscopy and to compare capillary patterns in different disease groups. Methods: The study included 200 patients diagnosed with rheumatological diseases and 50 healthy volunteers. The nail bed capillaries of all participants were evaluated using a digital dermatoscope. Capillary examination assessed the presence of edema, tortuous, elongated, dilated, and brush-like capillaries, microhemorrhages, and avascular areas. Statistical analyses were performed using appropriate parametric and non-parametric tests, and a P value < 0.05 was considered statistically significant. Results: The frequency of capillary abnormalities was significantly higher in the patient group than in the control group. The most frequently observed findings were edema and tortuous, elongated capillaries. Capillary patterns differed by disease group, with more specific findings particularly prominent in patients with systemic sclerosis. Conclusion: Nail capillaroscopy is an effective, easily applicable, and non-invasive method for evaluating microvascular changes in rheumatological diseases. Capillary patterns observed in different disease groups can provide clinically valuable information for diagnosis and disease monitoring.

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• ArticleAçık Erişim2023/r/ebyu/20260
  The investigation of dermatophyte agents in patients with dermatophytosis diagnosis

  Melikoglu, Mehmet; Ozdemir, Sevki; Uslu, Hakan

  The aim of our study was to investigate the features and agents in patients with dermatophytosis and to evaluate the dermatophyte flora changes in our area in recent years. Patients and Methods: Patients with dermatophytosis were included in our study. The age, gender, social life area, animal contact history of the patients and the clinical types of dermatophytosis were recorded. 443 native preparation positive species were cultured and their pathogens were investigated. There were 367 cases with an age range between 1-79 years. The animal contact history was present in 23,7% and rural area living anamnesis was present in 21.2% of the species having dermatophytosis diagnosis. The ratio of clinical type distributions were determined as follows; T.pedis %41.5, T.unguium on foot+hand %29.2, T.capitis %9.9, T.inguinalis %7.2, T.corporis %6.1, T.manum %3.6, T.facialis %2.0 and T.barba %0.5. The agent could be identified in 76.5% of the species with the rates of T.rubrum 62.5%, T.mentagrophytes 16.8%, T.verrucosum 9.4%, M.canis 4.7%, E.floccosum 3.2%, T.violaceum 1.8%, T.tonsurans 0.9%, M.nanum 0.3 % and T.schonlein 0.3 %. T.rubrum was the most frequent agent causing T.pedis, T.unguium, T.inguinalis. Also T.verrucosum was the most frequent agent in T.capitis, T.corporis and T.barba and it was considered that this could be arised from our animal husbandry region. There have been differentiations in dermatophytosis and their agents today versus their status in 20 years ago in our region. Although they were decreased in comparison to the past, cases with T. capitis have remained their importance at present.

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• ArticleAçık Erişim2022/r/ebyu/20640
  Prevalence and density of Demodex mites (Acari: Demodecidae) in patients with seborrheic dermatitis

  Zeytun, Erhan; Yazıcı, Mustafa

  This study was conducted to determine the prevalence and density of Demodex mites in patients with seborrheic dermatitis. The study included 37 patients and 35 healthy controls who were diagnosed with seborrheic dermatitis by clinical examination. The sample materials were taken from the cheek, nasolabial and jaw areas of the participants using the standard superficial skin biopsy method and examined for the presence and number of Demodex mites under light microscopy. Demodex spp. mites were detected in 34 (91.9%) of the patients and in 20 (60%) of the controls. Demodex folliculorum was detected in 34 of 37 patients (mean 15.7/cm2; total 535) and D. brevis (mean 0.6/cm2; 20 total) in six patients. Demodex folliculorum was detected in 20 of 35 healthy controls (mean 2.7/cm2; total 56) and D. brevis (mean 0.5/cm2; total 1) in one of the 35 healthy controls. When patients and controls were compared in terms of Demodex prevalence and density, the differences were statistically significant. In conclusion, Demodex mites are more prevalent in patients with seborrheic dermatitis in Erzincan Province of Turkey. This condition may be related to the amount of sebum in patients with seborrheic dermatitis, however, this issue should be supported by further studies in which sebum levels are measured and ilarger number of patients are involved.

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• ArticleAçık Erişim2022/r/ebyu/20343
  Evaluation of Quality of Life, Anxiety and Depression in Patients\rwith Recurrent Aphthous Stomatitis

  Öner, Ümran; Ozdemir, Sevki; Kurt, Osman; Öner, Fatih

  Objective: Recurrent aphthous stomatitis (RAS) is one of the most common diseases of the oral mucosa characterized by recurrent painful\roral ulcers. We evaluated the effect of RAS on quality of life and the relationship between RAS and anxiety and depression.\rMethods: The study involved 70 patients (35 female, 35 male) with RAS and 70 healthy volunteers (32 females, 38 males) who matched the\rpatients with age and gender. Demographic features and medical histories of individuals were recorded. Patients and controls filled out the\rdermatology quality of life index (DLQI) and the hospital anxiety and depression scale (HADS). The results were compared statistically.\rResults: The DLQI score of RAS patients was significantly higher than the control group [p<0.001, interquartile range (IQR): 6.0-15.0 vs.\r2.0-9.0]. DLQI score for the patients during the active phase was significantly higher than that for the patients during the remission period\r(p=0.039, IQR: 6.5-16.0 vs. 2.0-10.0). There was no significant difference in HAD score between the groups (p>0.05).\rConclusion: The results of our study show that there is no relationship between RAS and anxiety and depression. However, RAS significantly\rdecreases the quality of life, particularly during the active phase.

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• ArticleYalnız künye2022/r/ebyu/20108
  Akne Vulgaris Hastalarında Sistemik İzotretinoinin Enflamatuvar Belirteçlere Etkisi

  Ozdemir, Sevki; Karaali, Muge Gore

  Amaç Literatürde izotretinoinin ( hem enflamatuvar hem de antienflamatuvar etkileri bildirilmiştir ve bu konuda çelişkili sonuçlar vardır Çalışmamızdaki amacımız akne vulgaris nedeni ile İZO tedavisi başlanan hastaların takibinde enflamatuvar belirteçleri değerlendirmektir Gereç ve Yöntem Dermatoloji polikliniğinde akne vulgaris tanısı ile sistemik İZO başlanan 75 hasta prospektif olarak değerlendirildi Hastaların demografik özellikleri kaydedildi, başlangıç ve tedavi takibinin 2 ve 6 ayında akne şiddeti Global Akne Değerlendirme Ölçeği ile hesaplandı Serum ürik asit, trombosit ( nötrofil lenfosit oranı ( trombosit lenfosit oranı ( monosit HDL kolesterol oranı ( albümin fibrinojen oranı ( ve CRP albümin oranı ( veri tabanına kaydedildi En az altı aylık İZO tedavisini tamamlayan 43 hasta üzerinden çalışma tamamlandı Bulgular Çalışmaya dahil edilen 43 hastanın 74 40 ’ı ( 32 kadın, 25 60 ’ı ( 11 erkek olup yaş ortalamaları 21 27  5 10 yıl idi Hastaların serum ürik asit, PLT, MHR, NLR, PLR, CAR enflamasyon parametreleri ortalama puanlarında tedavi takibinde başlangıç değerlerine göre anlamlı fark olmadığı saptandı ( 0 05 Hastaların AFR ortalama puanlarında zaman içinde anlamlı fark olduğu, 2 ay ve 6 ay AFR ortalama puanlarının 0 ay AFR ortalama puanlarından daha düşük olduğu belirlendi ( 0 06 Enflamasyon parametreleri ile akne şiddeti arasında anlamlı bir korelasyon saptanmadı Sonuç AFR, İZO’nun sistemik enflamasyon göstergesi olarak kullanılabilecek bir belirteç olabilir Bu konuda daha geniş serili çalışmalara ihtiyaç vardır

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