Sürdürülebilir Kalkınma Amaçları
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- ArticleAçık Erişim2026The Relationship Between Non-alcoholic Fatty Liver Disease and Epicardial Adipose Tissue Thickness, Carotid Intima Media Thickness, and Aortic Propagation Velocity
Aydin, Sonay; Ozcicek, Fatih; Hayme, Serhat; Coşgun, Muharrem Said; Ozturk, Ersin; Öztürk, Gülay Kızılgün
Objective: Cardiovascular disease is prevalent among individuals diagnosed with non-alcoholic fatty liver disease (NAFLD). Epicardial adipose tissue (EAT), carotid intima-media thickness (CIMT), and aortic propagation velocity (APV) are associated with atherosclerosis and cardiovascular disease (CVD). The aim of this study is to determine whether NAFLD is associated with EAT, CIMT, and APV. Methods: Individuals aged ≥18 and <65 years who presented for routine follow-up were included. The study population comprised 75 healthy controls (40 females, 35 males) and 141 patients with NAFLD (68 females, 73 males). Epicardial adipose tissue thickness, carotid intima-media thickness, and aortic propagation velocity were evaluated using transthoracic echocardiography in patients who were diagnosed with hepatosteatosis by ultrasound during routine check-ups at the internal medicine clinic. Results: NAFLD was positively associated with epicardial adipose tissue thickness and carotid intima–media thickness, and negatively associated with aortic propagation velocity. Patients with NAFLD had significantly higher EAT and CIMT values and lower APV values than controls. Logistic regression analysis identified body mass index (BMI) and EAT as independent predictors of hepatosteatosis. Each unit increase in BMI was associated with a 1.29-fold increase in the risk of hepatosteatosis, whereas each unit increase in EAT was associated with a 5.49-fold increase. Conclusion: Given the established associations of CIMT, APV, and EAT with atherosclerosis and cardiovascular disease, assessment of patients with NAFLD using these noninvasive parameters may help identify subclinical cardiovascular risk.
RDL Kalıcı Kaydıİncele - ArticleAçık Erişim2026Assessment of Potentially Unnecessary Breast Magnetic Resonance Imaging Utilization and Its Economic Impact: A Retrospective Study
Senbil, Duzgun Can; Kiliçparlar, Muslum Burak; Kantarci, Mecit; Aydin, Sonay
Background: In this study, breast magnetic resonance imaging (MRI) examinations were retrospectively reviewed. This study evaluated whether the indications for breast MRI were consistent with the recommendations of the Breast Imaging Reporting and Data System (BI-RADS)atlas. Additionally, the study assessed whether prior ultrasound and mammography findings were sufficient for diagnosis. The aim was to identify potentially unnecessary breast MRI examinations and their associated financial burden. Methods: Breast MRI reports were compared with previous mammography and ultrasound reports. Patients for whom breast MRI provided no additional diagnostic benefit were identified, and the indications for MRI examination were analyzed. Results: Comparison of BI-RADS categories assigned on prior ultrasound and mammography with those assigned after breast MRI revealed that 321 (64.3%) of the 499 patients could have been adequately managed without breast MRI. In these patients, MRI findings did not alter clinical management or treatment decisions. Conclusion: Breast MRI is a costly imaging modality with limited accessibility in many healthcare settings. Therefore, its economic impact should be carefully considered when determining appropriate indications for its use. These findings suggest that the absence of restrictive criteria for breast MRI requests may contribute to substantial financial losses due to unnecessary examinations.
RDL Kalıcı Kaydıİncele - ArticleAçık Erişim2026A rare cause of portal vein thrombosis: Fascioliasis
Aydin, Sonay; Kyzy, Zulaika Askarbek; Memis, Kemal Bugra
RDL Kalıcı Kaydıİncele - Review ArticleAçık Erişim2025Çocuk İstismarı: Acil Radyolojide Akılda Bulunması Gerekenler
Aydin, Sonay; Uner, Cigdem; Oztepe, Muhammet Fırat
Çocuk istismarı, acil radyolojide erken tanı ile hayat kurtarabilen ciddi bir sorundur. Acil radyoloji pratiğinde, istismar şüphesine yönelik bulguların dikkatlice ve erkenden saptanması hayat kurtarıcıdır. Fiziksel istismar en sık kranial bölge, iskelet sistemi ve organ yaralanmaları ile bulgu verirler. Şüpheli bulguların doğru şekilde raporlanması ve ilgili birimlere bildirilmesi yasal bir zorunluluktur.
RDL Kalıcı Kaydıİncele - Review ArticleAçık Erişim2025The Role of Imaging Methods in the Diagnosis and Treatment of Idiopathic Granulomatous Mastitis
Aydin, Sonay; Kantarci, Mecit; Aydemir, Hüseyin
Idiopathic granulomatous mastitis (IGM) is an uncommon chronic inflammatory disease of the breast with an unclear etiology that mostly impacts young women. Its incidence is higher in the Middle East and Asian countries, particularly in Türkiye. Clinical signs such as mass, fistula formation, swelling, and radiographic abnormalities such as lymph node enlargement, abscess, calcifications, localized or widespread asymmetric density, and hypoechoic lesions may result in a misdiagnosis of malignancy or infection. There are no imaging findings that distinguish between IGM and breast cancer in any imaging method; in most cases, imaging tests like ultrasonography, magnetic resonance imaging, or mammography reveal non-specific characteristics, leading to biopsy. Histological assessment is used to reach a conclusive diagnosis of IGM. Common medical treatments include systemic steroid treatment (oral corticosteroid), local steroid treatment (local steroid injection in breast,), antibiotics, immunosuppressive drugs (methotrexate, etc.), and monoclonal antibodies. Abscess drainage and surgical excision are further alternatives. Although the conclusive diagnosis of IGM is made histologically, imaging methods have a significant impact in evaluating the number, location, their size, abscess development, and the likelihood of intervention, stability or change in lesions, and response to treatment in patients with confirmed diagnosis. In addition, radiology and interventional radiology units guide clinicians in the timely diagnosis of the disease and play an important role in local steroid injection, which is used effectively in its treatment.
RDL Kalıcı Kaydıİncele - ArticleAçık Erişim2025Incidental brain MRI findings in intensive care unit patients: a retrospective analysis
Aydin, Sonay; Taş, Necip Gökhan; Taş, Hakan Gökalp
Aims: Magnetic resonance imaging (MRI) frequently shows unexpected results unrelated to the presumed pathology. The aim of this study is to look into the frequency and type of incidental brain MRI findings in ICU patients. Methods: The Anesthesiology and Reanimation Intensive Care Unit at Erzincan Mengücek Gazi Training and Research Hospital was the setting for the retrospective observational study. A total of 5,145 ICU patients admitted between 2021 and 2023 were screened using the hospital information management system, eliminating those without a brain MRI. Incidental findings in brain MRI data were documented and divided into five categories: vascular (aneurysms, cavernomas, and other vascular structures), neoplastic (meningioma, pituitary mass, glioma, and other tumors), Chiari malformation, pineal cyst, and arachnoid cyst. Results: 1317 (25.6%) participants who received brain MRI were included in the study. Incidental MRI findings were detected in 366 patients (27.8%). The most common incidental discoveries were vascular anomalies (9.79%, primarily aneurysms and cavernomas), neoplastic lesions (8.81%, primarily meningiomas and pituitary masses), arachnoid cysts (2.89%), nonspecific plaques (2.81%), pineal cysts (2.66%), and Chiari malformations (0.84%). A large majority of these patients had clinically important findings that demanded additional clinical follow-up or evaluation; nevertheless, none required emergency surgical intervention. Patients with incidental findings had a mean age of 70.92±18.42 years (range 18-98). Conclusion: In conclusion, incidental MRI results are common in critically ill patients and have significant clinical consequences. Enhanced clinician awareness and consistent management practices are critical for improving patient care, reducing unnecessary interventions, and optimizing results. Future prospective studies are required to create tailored guidelines for this population.
RDL Kalıcı Kaydıİncele - ArticleAçık Erişim2025Association between insall-salvati index and anterior cruciate ligament tears: A cross-sectional study
Kizilgöz, Volkan; Aydin, Sonay; Kantarci, Mecit; Kockara, Nizamettin; Gülmez, Ali Osman; Gür, Volkan
Aim: There are many studies in the literature presenting morphological predisposing factors of anterior cruciate ligament (ACL) tears. Insall-Salvati index (ISI), which is widely used to measure patellar height, was investigated as a predisposing risk factor for the ruptures of ACL. Material and Methods: Patellar tendon length (PTL), Patellar length (PL), and anterior tibial translation (ATT) were measured, and ISI values were calculated for the study and control groups. Knee magnetic resonance (MR) images of 33 patients who had undergone ACL reconstruction due to ruptured ACL, which is surgically confirmed (study group), and 90 patients who had undergone meniscus operation with surgically confirmed intact ACL (control group) were reinterpreted by two reviewers in terms of ISI and ATT values. Independent samples T-test was used to compare the results of the study and control groups. Additionally, intraclass correlation coefficient (ICC) values were presented to verify the interobserver difference between reviewers. Results: PTL, ATT, and ISI values showed a statistically significant difference, and higher values were obtained in the study group than in the control group (p<0,001). There was excellent agreement between reviewers regarding PTL, PL, ISI, and ATT measurements. Discussion: ISI had been used as an indicator of patellar dislocation. In this research, ISI was investigated to be in a relationship with ACL injuries in operated patients. The results of this study indicated higher ISI values in patients with ACL rupture. High ISI values might be a predisposing factor for ACL rupture and may be used in preventive medicine in terms of ACL injuries.
RDL Kalıcı Kaydıİncele - EditorialAçık Erişim2025Rectal ameboma: A new entity in the differential diagnosis of rectal cancer
Memis, Kemal Bugra; Celik, Ayse Sena; Aydin, Sonay; Kantarci, Mecit
We examined the case report written by Ke et al, describing a rare clinical case. In this editorial, we would like to emphasize the differential diagnosis of rectal masses through a rare case. We describe a case of ameboma, which manifested itself as a mass in the rectum in terms of imaging and rectoscopic features, in an immunocompetent patient who had complaints of constipation and rectal bleeding for weeks. The initial diagnosis suggested malignancy due to imaging and rectoscopic features, but the pathology report reported it as amoebiasis. After ten days of metronidazole and oral amebicide (diloxanide furoate) treatment, the patient's symptoms and radiological findings were successfully regressed.
RDL Kalıcı Kaydıİncele - Review ArticleAçık Erişim2025Role of imaging in chronic otitis media and its complications
Memis, Kemal Bugra; Aydin, Sonay
Chronic otitis media (COM) is a long-standing inflammatory condition affecting the middle ear and mastoid cavity, often resulting in progressive structural damage and functional deficits. Radiological imaging is fundamental in diagnosing the disease, assessing its severity, and identifying possible complications. The literature indicates that the prevalence rates of extracranial and intracranial complications range from 0.69% to 5%, while the mortality rate for intracranial complications is 26%. While magnetic resonance imaging is particularly useful in distinguishing soft tissue abnormalities and detecting intracranial extensions like meningitis, brain abscess, and sigmoid sinus thrombosis, high-resolution computed tomography remains the preferred modality for evaluating bony erosion, cholesteatoma, and mastoid involvement. Key complications such as ossicular chain destruction, facial nerve damage, and labyrinthine fistulae can be precisely identified using advanced imaging modalities, allowing for timely and effective surgical intervention. This minireview underscores the essential role of radiology in both diagnosing and managing COM, highlighting critical imaging findings that facilitate early detection and inform treatment decisions. A collaborative approach among radiologists, otolaryngologists, and infectious disease specialists is crucial for improving clinical outcomes in affected patients.
RDL Kalıcı Kaydıİncele - ArticleYalnız künye2025Evaluation of Femoral Head Avascular Necrosis with Virtual Noncalcium Dual-Energy Computed Tomography
Ozturk, Muhsin Ozgun; Kantarci, Mecit; Aydin, Sonay; Kizilgöz, Volkan; Kockara, Nizamettin; Gur, Volkan
Objective Our aim was to investigate the effectiveness of the dual-energy computed tomography (DECT) virtual noncalcium (VNCa) technique in avascular necrosis (AVN) for detecting bone marrow edema (BME) and staging. Methods This prospective study included adult patients diagnosed with unilateral or bilateral femoral head AVN between January 2023 and December 2023, who had magnetic resonance imaging (MRI) and DECT. Two participants were excluded from the study due to undergoing surgical procedures during the period between the scans. Two reviewers, blinded to MRI images and clinical data, visually examined color-coded VNCa pictures to assess BME using a binary classification (0 = normal bone marrow, 1 = BME). Same 2 reviewers also used color-coded and nonmapped images to stage AVN in accordance to the "Association for Research on Osseous Circulation"(ARCO) staging system. Interobserver agreements for the visual evaluation and staging were calculated with κ coefficient. Following a visual assessment of BME and the staging of AVN, same 2 reviewers conducted CT density measurements on regions of BME regions utilizing DECT noncalcium images. An independent third investigator (reference standard) utilized MRI, x-ray, and clinical data to confirm the definitive diagnosis and staging of AVN. A P value less than 0.05 was considered statistically significant. Results Fifty patients (28 men, 22 women, mean age: 44.2 ± 13.1 years, range: 25-75 years) were included in the final analysis. The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of the VNCa technique in detecting BME were 96.0%, 94.4%, 97.9%, 89.4%, and 95.6%, respectively, for reviewer 1; and 96.0%, 88.9%, 96.0%, 88.9%, and 94.1%, respectively, for reviewer 2. Interobserver agreement was almost perfect (κ = 0.84). Both reviewer 1 and reviewer 2 accurately classified 92.7% of the AVNs. The density measurements showed a statistically significant difference (P = 0.001) between the edema regions and the normal marrow regions. No statistically significant difference was observed in the density measurements of edema regions at different stages (P = 0.13). Conclusions DECT VNCa technique exhibits excellent performance in detecting BME in hip AVN cases, as well as accurately determining the stage of AVN.
RDL Kalıcı Kaydıİncele - ArticleAçık Erişim2025Relationship Between Sigmoid Volvulus Subtypes, Clinical Course, and Imaging Findings
Memis, Kemal Bugra; Aydin, Sonay
Background: Recent studies indicate that the organo-axial subtype of a sigmoid volvulus is more prevalent than the conventional mesentero-axial subtype. Our study aimed to assess the clinical and radiological findings that differentiate between these two subtypes, as well as to ascertain treatment outcomes and prognostic characteristics. Methods: A retrospective review included 54 patients, during which abdominal plain radiographs and computed tomography images were analyzed by two radiologists, and data on recurrence, mortality, and treatment outcomes were documented. Results: The mesentero-axial subtype comprised 40 cases (74%). No distinct radiographic findings were observed to differentiate between the two groups. In computed tomography, the sole significant parameter for differentiation was the number of transition zones. The diameter of the segment exhibiting a volvulus was greater in instances of the mesentero-axial subtype. The endoscopic detorsion treatment proved ineffective in five patients within the mesentero-axial sigmoid volvulus cohort. Conclusions: Identifying these two types of SV on CT images is essential because of their distinct prognoses and therapeutic results.
RDL Kalıcı Kaydıİncele - ArticleAçık Erişim2025Early Detection of Lung Metastases in Breast Cancer Using YOLOv10 and Transfer Learning: A Diagnostic Accuracy Study
Taş, Hakan Gokalp; Taş, Mehmet Bilge Han; Yildiz, Eyyup; Aydin, Sonay
Background: This study used CT imaging analyzed with deep learning techniques to assess the diagnostic accuracy of lung metastasis detection in patients with breast cancer. The aim of the research was to create and verify a system for detecting malignant and metastatic lung lesions that uses YOLOv10 and transfer learning. Material/Methods: From January 2023 to 2024, CT scans of 16 patients with breast cancer who had confirmed lung metastases were gathered retrospectively from Erzincan Mengücek Gazi Training and Research Hospital. The YOLOv10 deep learning system was used to assess a labeled dataset of 1264 enhanced CT images. Results: A total of 1264 labeled images from 16 patients were included. With an accuracy of 96.4%, sensitivity of 94.1%, specificity of 97.1%, and precision of 90.3%, the ResNet-50 model performed best. The robustness of the model was shown by the remarkable area under the curve (AUC), which came in at 0.96. After dataset tuning, the GoogLeNet model’s accuracy was 97.3%. These results highlight our approach’s improved diagnostic capabilities over current approaches. Conclusions: This study shows how YOLOv10 and transfer learning can be used to improve the diagnostic precision of pulmonary metastases in patients with breast cancer. The model’s effectiveness is demonstrated by the excellent performance metrics attained, opening the door for its application in clinical situations. The suggested approach supports prompt and efficient treatment decisions by lowering radiologists; workload and improving the early diagnosis of metastatic lesions.
RDL Kalıcı Kaydıİncele - Review ArticleAçık Erişim2025Emergency radiology: roadmap for radiology departments
Aydin, Sonay; Ece, Bunyamin; Cakmak, Vefa; Kocak, Burak; Onur, Mehmet Ruhi
Emergency radiology has evolved into a significant subspecialty over the past 2 decades, facing unique challenges including escalating imaging volumes, increasing study complexity, and heightened expectations from clinicians and patients. This review provides a comprehensive overview of the key requirements for an effective emergency radiology unit. Emergency radiologists play a crucial role in real-time decision-making by providing continuous 24/7 support, requiring expertise across various organ systems and close collaboration with emergency physicians and specialists. Beyond image interpretation, emergency radiologists are responsible for organizing staff schedules, planning equipment, determining imaging protocols, and establishing standardized reporting systems. Operational considerations in emergency radiology departments include efficient scheduling models such as circadian-based scheduling, strategic equipment organization with primary imaging modalities positioned near emergency departments, and effective imaging management through structured ordering systems and standardized protocols. Preparedness for mass casualty incidents requires a well-organized workflow process map detailing steps from patient transfer to image acquisition and interpretation, with clear task allocation and imaging pathways. Collaboration between emergency radiologists and physicians is essential, with accurate communication facilitated through various channels and structured reporting templates. Artificial intelligence has emerged as a transformative tool in emergency radiology, offering potential benefits in both interpretative domains (detecting intracranial hemorrhage, pulmonary embolism, acute ischemic stroke) and non-interpretative applications (triage systems, protocol assistance, quality control). Despite implementation challenges including clinician skepticism, financial considerations, and ethical issues, AI can enhance diagnostic accuracy and workflow optimization. Teleradiology provides solutions for staff shortages, particularly during off-hours, with hybrid models allowing radiologists to work both on-site and remotely. This review aims to guide stakeholders in establishing and maintaining efficient emergency radiology services to improve patient outcomes.
RDL Kalıcı Kaydıİncele - ArticleAçık Erişim2025Thyroid Imaging Reporting and Data System on the Basis of Cost and Effectiveness
Aydin, Sonay; Gulmez, Ali Osman; Memis, Kemal Bugra
Background: We aim to evaluate thyroid imaging reporting and data system (TIRADS) on the basis of cost and effectiveness through the numbers of fine‑needle aspiration biopsies (FNABs) and sonographic examinations in a tertiary health‑care institution. Methods: The 50‑day intervals before and after the start of TIRADS use (October 10, 2022) were evaluated to carry out this assessment. The reason for choosing 50‑day periods was because it covers the initial phase when the study is most optimally performed in our hospital. The number of thyroid ultrasound (US) and FNAB procedures carried out in our facility during that time was tallied. Exclusion standards were not applied. Results: One thousand nine hundred eighty‑two people made up the study population. Fifty days before the October 10, 2022, there were 975 instances (49.2%), and 50 days after that, there were 1007 cases (50.8%). Out of 1982 cases, it was discovered that 190 (9.6%) underwent a biopsy, and 1792 (90.4%) underwent a US examination. It was found that the first period’s rate of biopsy examination was significantly higher than the second period’s rates of 11.1% and 8.1%, respectively. The rate of biopsy examination in males during the first period was found to be substantially higher than the second period. Individuals between the ages of 35 and 50 years had a rate of biopsy examination that was considerably higher in the first period than the second period. Conclusion: The TIRADS Risk Scale has the capacity to reduce unnecessary biopsies, hence mitigating potential psychological distress, burden, and financial expenses for the patient.
RDL Kalıcı Kaydıİncele - ArticleAçık Erişim2025Echinococcus granulosus in atypical localizations: Five case reports
Celik, Ayse Sena; Yosunkaya, Hacer; Ozyilmaz, Aysel Yayilkan; Memis, Kemal Bugra; Aydin, Sonay
BACKGROUND Hydatid cyst disease, caused by Echinococcus granulosus, primarily affects the liver and lungs, but it can also develop in rare locations such as the kidneys, thyroid, subcutaneous tissues, bones, and the mediastinum. These atypical presentations often pose diagnostic challenges, as they can mimic benign and malignant pathologies, leading to potential misdiagnoses and inappropriate treatments. Early and accurate detection of hydatid cysts in uncommon sites is crucial for optimal patient management. CASE SUMMARY This case report series presents five patients with hydatid cysts located in atypical anatomical regions: The kidney, lumbar subcutaneous tissue, gluteal soft tissue, posterior mediastinum, and thyroid gland. The patients exhibited diverse clinical symptoms, including hematuria, palpable masses, localized pain, and chronic cough. Diagnosis was confirmed through a combination of imaging techniques-ultrasound, computed tomography, and magnetic resonance imaging-along with serological testing. All cases were managed with antiparasitic therapy (alben-dazole), and in selected cases, surgical excision was performed to prevent complications such as cyst rupture or secondary infections. Post-treatment follow-up demonstrated complete resolution or stable cystic lesions, with no signs of recur-rence. CONCLUSION Recognizing hydatid cysts in atypical locations is essential to avoid misdiagnosis and ensure appropriate treatment strategies. Radiological imaging plays a key role in distinguishing hydatid cysts from other cystic and neoplastic conditions, while serological tests can aid in confirmation, particularly in endemic regions. A multidisciplinary approach, integrating radiology, clinical evaluation, and surgical expertise, is critical for effective diagnosis and management. This report highlights the need for increased awareness of extrapulmonary and extravisceral hydatid disease, emphasizing its significance in differential diagnosis and clinical practice.
RDL Kalıcı Kaydıİncele - ArticleAçık Erişim2025The Ovarian Volume in Girls Presented as Precocious Puberty
Durmaz, Onder; Fatihoglu, Erdem; Hatun Ozkan, Berna; Bugra Memis, Kemal; Aydin, Sonay
Background: Isosexual precocious puberty (PP) is defined as the appearance of secondary sexual characteristics before the age of 8 years in girls and before the age of 9 years in boys. The aim of this study was to evaluate the association of ovarian volume and bone age measurements with the number of symptoms in female patients diagnosed with PP. Methods: The dataset includes pelvic ultrasound and bone age tests from 96 girls diagnosed with PP who presented to a tertiary hospital’s pediatric outpatient clinic with signs and symptoms of early puberty between January 1, 2020, and January 1, 2021. The study included 96 healthy ladies of the same age as a control group. Results: A total volume >2.75 was shown to predict the existence of pubertal pre with 79.2% sensitivity and 90.6% specificity (area under the curve [AUC]: 0.903; P = 0.001). A total volume of >3.25 predicted the existence of 2 or more symptoms in patients with PP, with a sensitivity of 72.1% and a specificity of 98.1% (AUC: 0.917; P = 0.001). Conclusion: To the best of our knowledge, no study has been published that investigates the relationship between the number of symptoms at the time of presentation and ovarian volume and bone age in girls with PP. Our investigation, which involved 192 female participants (96 patients and 96 controls), revealed a statistically significant correlation between the frequency of symptoms indicating early puberty and a rise in both ovarian capacity and bone age.
RDL Kalıcı Kaydıİncele - ArticleAçık Erişim2025Incidental Calcifications of Carotid and Vertebral Arteries: Frequency and Associations in Pediatric Population
Cetin, Turkhun; Cinar, Gokce; Ucan, Berna; Memis, Fulya; Irgul, Baris; Aydin, Sonay
Background: Calcifications in the carotid and vertebral arteries may be present on cranial and temporal bone CT imaging of pediatric patients. Few studies have investigated the frequency, location, and patterns of carotid artery calcifications in this age group. However, these studies are outdated and do not include data on the vertebral artery. The aim of this study was to determine the frequency, location, and pattern of incidental carotid and vertebral artery calcifications on cranial CT and temporal bone CT images in children under 15 years of age. We also aimed to investigate possible associations between these calcifications and various diseases. Methods: A total of 300 CT images of the cranial and temporal bone of 300 pediatric patients were retrospectively evaluated for the presence of calcification in the carotid and vertebral arteries. The evaluation included determining the presence of calcification in the artery, the pattern of calcification, the degree of calcification, and its anatomical location. Results: In the current study, 300 CT images were analyzed, and calcifications were found in the vertebral artery in 17 patients (5.6%) and the carotid artery in 82 patients (27.3%). The supraclinoid segment and the carotid siphon regions are the most common locations of carotid artery calcifications, with 62 patients (20.7%). The V4 segment is also the most common location for vertebral artery calcifications, with 15 patients (5%). Focal punctate calcification is the most common pattern (65 patients, 21.7%). Incidental carotid and vertebral artery calcifications did not correlate with other diseases. Conclusions: Carotid and vertebral artery calcifications are common incidental findings in pediatric patients. In our study, no association was found between other diseases and incidental carotid and vertebral artery calcifications.
RDL Kalıcı Kaydıİncele - ArticleAçık Erişim2025Relationship Between Ocular Trauma Score and Computed Tomography Findings in Eyes with Penetrating Globe Injuries: A Preliminary Study
Durmuş Ece, Berire Şeyma; Yozgat, Zübeyir; İnançlı, Yusuf; Ece, Bunyamin; Aydin, Sonay
Background/Objectives: The aim of this study was to evaluate computed tomography (CT) findings in penetrating globe injuries and their relationship with ocular trauma scores (OTSs). Methods: Patients with penetrating globe injuries who had orbital CT images were included in this study. Demographics, injury zone, and ophthalmologic exam data were collected retrospectively. OTSs and categories were determined. Orbital CT images were evaluated by a radiologist to determine decreased globe volume, globe wall irregularity, chorioretinal layer thickening, lens dislocation, asymmetric anterior chamber depth (ACD), abnormal vitreous density, and intraocular air presence. Results: This study included 30 eyes of 30 patients. The majority of patients (n = 20, 66.7%) had Zone I injuries. The most common CT findings were globe wall irregularity (53.3%) and asymmetric ACD (53.3%). No CT findings were observed in 10 patients (33.3%). Globe wall irregularity was the most frequent CT finding in the OTS II category, while asymmetric ACD was most frequent in the OTS IV category. All patients with decreased globe volume, lens dislocation, abnormal vitreous density, and ≥3 CT findings were in the OTS II category. A significant negative correlation was found between the number of CT findings and OTS (r = −0.644, p < 0.001), and a significant positive correlation was found between the number of CT findings and clinically measured wound size (r = 0.600, p < 0.001). Conclusions: CT findings help assess ocular trauma severity, but clinical examination remains essential for accurate diagnosis.
RDL Kalıcı Kaydıİncele - ArticleAçık Erişim2025Evaluation of Lacrimal Drainage System in Patients with Unilateral Nasolacrimal Duct Obstruction by Computerized Tomography
Kazanci, Burcu; Gokharman, Dilek; Aydin, Sonay; Eroğlu, Fatma Çorak; Apaydin, Nihal
Purpose: This study aimed to evaluate morphometric measurements relevant for surgery in patients with unilateral nasolacrimal duct occlusion on CT images, comparing the sides with and without occlusion. Methods: Paranasal sinus computed tomography images of 37 patients (28 females, 9 males) who presented with unilateral epiphora and underwent external dacryocystorhinostomy were retrospectively analyzed. Two radiologists with 25 and 10 years of experience performed measurements. The nasolacrimal duct length, transverse diameter of its narrowest part, vertical length of the lacrimal fossa, thickness of the anterior lacrimal crest, its distance to anterior ethmoidal cells, thickness of the intranasal lateral mucosa, frontonasal angle, and distance between the frontozygomatic sutures were measured and compared bilaterally. Results: The narrowest diameter of the nasolacrimal duct on the occluded side was significantly narrower than on the intact side. There were no significant differences between the occluded and patent sides for other measurements or the interclass correlation results between the two radiologists’ evaluations. Conclusion: Stenosis of the nasolacrimal duct on both sides is observed clinically as chronic dacryocystitis in the same patient. Since the bony window for external dacryocystorhinostomy is determined based on the lacrimal fossa’s vertical width, the data from our study are crucial for surgical planning.
RDL Kalıcı Kaydıİncele - ArticleAçık Erişim2025Evaluation of Interleukin-10, Vascular Endothelial Growth Factor Levels, and Bone Marrow Parameters in Multiple Myeloma Patients at Diagnosis and After Treatment
Memis, Fulya; Kandefer, Meryem Yalvac; Aydin, Sonay; Dalva, Klara; Toprak, Selami Kocak
Background: Interleukin-10 (IL-10) and vascular endothelial growth factor (VEGF) are believed to possess a role in the pathophysiology of multiple myeloma (MM). We aimed to assess the significance of these parameters in the diagnosis, monitoring, and prognosis of the disease by examining them in patients at diagnosis and post-treatment and comparing the findings with those of healthy individuals. Methods: We conducted blood sampling from 35 patients diagnosed with MM at the time of diagnosis and from 15 of these patients post-treatment. We additionally assessed similar serum markers in a control group of 15 healthy individuals. Furthermore, we documented laboratory results, organ involvement, comorbidities, and CD27-CD81 levels assessed using flow cytometry in the bone marrow, along with treatments and patient responses. We also examined the quantity of cells collected during mobilization in patients who had autologous stem cell transplantation. Results: We found a positive correlation (p = 0.028/p = 0.035) between IL-10 and VEGF with the international staging score. In patients with renal involvement, IL-10 levels were higher and VEGF levels were lower than those without renal involvement (p = 0.011/p = 0.012). We showed that VEGF levels decreased significantly with treatment (p = 0.001). We found no statistically significant correlation between treatment responses and IL-10 and VEGF. The number of CD34 cells collected by mobilization showed a negative correlation with CD27 and a positive correlation with VEGF (p = 0.007/p = 0.032). Conclusions: Serum IL-10 level is associated with ISS and renal involvement in MM patients. There is a positive correlation between serum VEGF levels and the number of stem cells collected during mobilization. As CD27 expression increases, the number of stem cells collected in mobilization decreases.
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