Anti-Alzheimer, antidiabetic and antioxidant potential of Satureja cuneifolia and analysis of its phenolic contents by LC-MS/MS

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Many chronic diseases such as diabetes and Alzheimer's disease are related to the type and quality of foods, which are consumed. Particularly, various plant origin products are stated as beneficial against such kind of chronic diseases with secondary metabolites such as their phenolic structures. Satureja cuneifolia is a plant, which is consumed as an herbal tea in some regions of Turkey and that's why investigate of its biological activity is important. In our study, the anti-diabetic and anti-Alzheimer potentials of the methanol and water extracts of S. cuneifolia plant were measured via some enzymes inhibition experiments as in vitro. The antioxidant ability of the same extracts was measured via radical scavenging and reducing power methods. Also, the total phenolics and flavonoids of the plant were identified. Finally, the extracts were analyzed by the LC-MS/MS analysis and the phenolic content of S. cuneifolia was clarified. © 2019 The Author(s)

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AlanDeğerDil
dc.contributor.authorTaslimi, Parham
dc.contributor.authorKöksal, Ekrem
dc.contributor.authorGören, Ahmet C.
dc.contributor.authorBursal, Ercan
dc.contributor.authorAras, Abdülmelik
dc.contributor.authorKılıç, Ömer
dc.contributor.authorAlwasel, Saleh
dc.contributor.authorGülçin, İlhami
dc.date.accessioned2026-10-18T20:28:48.448695527Z
dc.date.available2026-10-18T20:28:48.448695527Z
dc.date.issued2020
dc.description.abstractMany chronic diseases such as diabetes and Alzheimer's disease are related to the type and quality of foods, which are consumed. Particularly, various plant origin products are stated as beneficial against such kind of chronic diseases with secondary metabolites such as their phenolic structures. Satureja cuneifolia is a plant, which is consumed as an herbal tea in some regions of Turkey and that's why investigate of its biological activity is important. In our study, the anti-diabetic and anti-Alzheimer potentials of the methanol and water extracts of S. cuneifolia plant were measured via some enzymes inhibition experiments as in vitro. The antioxidant ability of the same extracts was measured via radical scavenging and reducing power methods. Also, the total phenolics and flavonoids of the plant were identified. Finally, the extracts were analyzed by the LC-MS/MS analysis and the phenolic content of S. cuneifolia was clarified. © 2019 The Author(s)
dc.description.sponsorshipS.A. would like to extend his sincere appreciation to the Researchers Supporting Projects (RSP-2019/59) at King Saud University for funding this research.
dc.identifier.doi10.1016/j.arabjc.2019.10.002
dc.identifier.endpage4537
dc.identifier.issn1878-5352
dc.identifier.issue3
dc.identifier.scopus2-s2.0-85074470091
dc.identifier.startpage4528
dc.identifier.urihttps://rdlopen.rawdatalibrary.net/r/ebyu/14011
dc.identifier.volume13
dc.language.isoen
dc.publisherElsevier B.V.
dc.relation.ispartofArabian Journal of Chemistry
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAnti-Alzheimer
dc.subjectAntidiabetic
dc.subjectAntioxidant activity
dc.subjectLC-MS/MS
dc.subjectSatureja cuneifolia
dc.subjectBioactivity
dc.subjectEnzyme inhibition
dc.subjectMetabolites
dc.subjectNeurodegenerative diseases
dc.subjectPlants (botany)
dc.subjectAlzheimer
dc.subjectAnti diabetics
dc.subjectAnti-oxidant activities
dc.subjectAntioxidants
dc.titleAnti-Alzheimer, antidiabetic and antioxidant potential of Satureja cuneifolia and analysis of its phenolic contents by LC-MS/MS
dc.typeArticle
dspace.entity.typePublication
rdl.citation.scopus158
rdl.oa.statusgold
rdl.source.indexSCOPUS