Araştırmacılar(13)
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37 →- ArticleYayıncıda açık erişim2026Association between monocyte/HDL cholesterol ratio and air pollution in a highly polluted region: A disease-specific analysis
Aydın, Muhammet Raşit; Karahan, Harun
The monocyte/HDL cholesterol ratio (MHR) is increasingly recognized as a potential marker of inflammation, oxidative stress, and endothelial dysfunction, despite the lack of standardized reference values. This study investigates the association between air pollution and MHR and its relationship with chronic diseases. A retrospective cohort study was conducted with 600 patients admitted to Igdir State Hospital. Patients were grouped by Particulate Matter 10 (PM10) exposure levels (≥50 μg/m³ vs <50 μg/m³). Laboratory data and disease diagnoses were recorded and analyzed. MHR was significantly higher in patients with atherosclerotic cardiovascular disease (ASCVD) (p<0.003) and lower in patients with diabetes mellitus (DM) (p<0.003) on days with PM10≥50 μg/m³. Similar trends were observed on low-pollution days (PM10<50 μg/m³), with a significant positive association between MHR and ASCVD (p<0.012) and cerebrovascular accident (CVA) (p<0.027). A significant correlation was also found between MHR and HbA1c levels (p<0.001). MHR is positively associated with cardiovascular risk and may serve as a low-cost, accessible marker of inflammation in clinical practice.
RDL Kalıcı Kaydıİncele - ArticleAçık Erişim2026Physicians’ perspectives on human papillomavirus vaccination in Türkiye through YouTube content analysis
Yanmaz, Gadime; Gursoy, Ersan
Background: Human papillomavirus (HPV) is a significant public health problem that is closely associated with various types of cancer, especially cervical cancer. Despite the proven effectiveness of HPV vaccines, misinformation and anti-vaccine rhetoric are widespread in the public, especially on social media platforms such as YouTube. In Türkiye, the HPV vaccine has not yet been included in the national immunization program, limiting its accessibility. Objective: The aim of this study is to analyze the opinions of physicians about the HPV vaccine in the most watched videos on YouTube in Türkiye and to reveal how expert opinions contribute to public awareness, correction of misinformation and guidance. Method: The 26 most watched HPV vaccine videos on YouTube produced by physicians in Türkiye were analyzed using thematic analysis. Videos were selected through searches using specific keywords (and their Turkish equivalents) such as “HPV vaccine”, “Should HPV vaccine be given?“, “Side effects of HPV vaccine”, “Is HPV vaccine harmful?” and “Cervical cancer vaccine” between February 2025 and April 2025. Only videos shorter than 20 min with physicians as the primary speakers and at least 1000 views were included. The verbal content of the physicians’ opinions in the videos were transcribed, and the analyzed videos were categorized under five main themes and six subthemes. Results: Physicians generally emphasized that the HPV vaccine is safe, effective, and necessary for both women and men. The types of vaccines, age of administration, side effects, and misconceptions among the public were discussed in detail. While there was a general consensus that the vaccine provides long-term protection, different views were expressed on whether it is effective for a lifetime. Physicians tried to correct misinformation in the videos and emphasize the importance of the vaccine in cancer prevention. Another important finding was that the fact that the vaccine was not included in the national vaccination program constituted a serious obstacle to access. Conclusion: Physicians play a critical role in delivering scientifically based health information to the public via social media. Expert content on digital platforms such as YouTube increases access to accurate information about the HPV vaccine and corrects misconceptions in the public. Findings indicate a pressing need for policy action to incorporate the HPV vaccine into the national immunization program and enhance expert visibility in combating misinformation on digital platforms.
RDL Kalıcı Kaydıİncele - ArticleAçık Erişim2026Patient vs. physician narratives on refractive surgery in Turkish YouTube videos: a comparative reflexive thematic analysis
Gürsoy, Nurcan; Gürsoy, Ersan
Correctable refractive errors are a major, preventable cause of visual impairment. Refractive surgery is widely promoted online, yet how Turkish-language YouTube videos frame benefits, risks, recovery, and long-term outcomes—and how this framing differs between patient and physician narrators—remains underexplored. We aimed to qualitatively compare patient- and physician-generated Turkish-language YouTube videos on refractive surgery and to describe audience engagement. We conducted a reflexive thematic analysis (Braun & Clarke) of 64 publicly available videos (29 patient, 35 physician) meeting predefined criteria (Turkish; primarily refractive surgery; ≥1 min; ≥1,000 views; ≥240p). Searches were performed on 15 July 2025 using predefined search strings. Videos were transcribed verbatim and inductively coded in NVivo by two researchers. Between-group differences in engagement metrics were assessed with Mann–Whitney U tests, with a one-video-per-channel sensitivity analysis to address potential clustering. Patient narratives foregrounded lived experience (decision-making, perioperative discomfort, postoperative visual fluctuations, and symptoms such as dry eye and glare/halos) and often raised concerns about commercialization. Physician narratives emphasized candidacy assessment, procedure selection, recovery timelines, and risk mitigation. In the one-video-per-channel sensitivity analysis (patient n = 27; physician n = 23), patient videos received more likes (median 300 [IQR 1,639] vs. 59 [269], p = 0.009) and showed a higher like-to-view ratio (0.013 [0.01] vs. 0.006 [0.01], p < 0.001), whereas view counts were not significantly different (24,000 [98,900] vs. 18,000 [48,500], p = 0.224). Turkish-language YouTube narratives share experiential touchpoints but diverge systematically in how risks, commercialization, and expectations are framed by patients versus physicians. Findings support the need for balanced, accurate, and discoverable patient-facing materials tailored to platform dynamics.
RDL Kalıcı Kaydıİncele - ArticleAçık Erişim2026Managing diagnostic uncertainty in primary care: a mixed-methods study of family physicians’ experiences in Türkiye
Nas, Mehmet Akif; Karahan, Harun; Gürsoy, Ersan
Background: Clinical uncertainty is an inherent component of primary care practice. Family physicians frequently face diagnostic ambiguity, time pressure, and limited access to diagnostic resources, which may affect decision-making and patient outcomes. However, evidence on how family physicians in Türkiye manage diagnostic uncertainty remains limited. Methods: This mixed-methods study included 20 family physicians practicing in primary care settings in Türkiye. Quantitative data were collected using the Physicians’ Reactions to Uncertainty Scale (PRUS) and the Melbourne Decision-Making Questionnaire I-II (MDMQ). Semi-structured interviews were then conducted and analyzed thematically using the Braun and Clarke framework. Results: Quantitative findings showed moderate-to-high emotional reactions to uncertainty and variation in decision-making styles among participants. Thematic analysis of the interviews revealed six key themes: diagnostic challenges and systemic barriers as major sources of uncertainty; specialist consultation, peer support, and patient communication as the main coping strategies; and the significant influence of patient compliance, physicians’ experience, and time pressure on decision-making. High patient load, referral difficulties, and inadequate digital systems were identified as major health system challenges. Physicians consistently emphasized the importance of case-based training and professional development, while also highlighting the role of transparent physician–patient communication in reducing uncertainty. Conclusions: Diagnostic uncertainty is a multifaceted challenge in primary care in Türkiye, influenced by individual, systemic, and patient-related factors. Strengthening case-based educational programs, improving referral processes, and reducing patient load may enhance physicians’ ability to manage uncertainty and improve patient outcomes. Clinical trial number: Not applicable.
RDL Kalıcı Kaydıİncele - ArticleYayıncıda açık erişim2026Living with Retinitis Pigmentosa in Türkiye: Diagnosis, Independence, and Access to Care
Gürsoy, Nurcan; Gürsoy, Ersan
Background: Retinitis pigmentosa (RP) is a progressive inherited retinal dystrophy that affects daily functioning, psychological well-being, and social participation. Although quantitative research describes disease burden, less is known about how individuals experience progressive vision loss in everyday life and within healthcare and social contexts. Methods: This qualitative study used semi-structured face-to-face interviews with adults diagnosed with RP. Purposive sampling was applied to ensure variation in demographic and clinical characteristics. Interviews were conducted in a tertiary ophthalmology clinic in Erzincan, Türkiye, between June and October 2025. Audio recordings were transcribed verbatim and analyzed using Braun and Clarke’s reflexive thematic analysis. Reporting followed the Consolidated Criteria for Reporting Qualitative Research (COREQ) checklist. Results: Sixteen participants (P1–P16) were included. Five themes were identified: (1) making sense of the illness and the diagnostic journey; (2) functional loss and the negotiation of independence; (3) psychological adaptation and identity reconstruction; (4) social relationships and social encounters; and (5) interaction with systems and the environment—accessibility and healthcare. Participants described early symptom normalization, delayed diagnostic pathways, and uncertainty persisting after diagnosis. Independence was shaped by safety concerns, environmental barriers, and reliance on support. Psychological adjustment fluctuated between fear of progression and efforts to sustain resilience. Social participation was influenced by support networks, concerns about being a burden, and stigma linked to invisible disability. Conclusions: Living with RP extends beyond visual impairment; building on prior qualitative work, our findings contextualize these experiences in Türkiye, highlighting how accessibility gaps, bureaucratic encounters in public institutions, and cost barriers within healthcare and public services can shape uncertainty, independence, and social participation.
RDL Kalıcı Kaydıİncele - ArticleYayıncıda açık erişim2025Approach to disasters by medical students in a disaster-affected region: Education and awareness
Gürsoy, Ersan; Gürsoy, Nurcan; Yağız, Mercan; Vatansever, Mehmet
This study aims to investigate the awareness of medical students, who are educated in regions that have experienced significant destruction from disasters such as earthquakes, towards disasters, the roles they can assume during disaster situations, and their attitudes towards disaster medicine. This cross-sectional study was conducted between November 2023 and January 2024 at Erzincan Binali Yıldırım University Faculty of Medicine, involving medical students aged 18 years and older. A structured, 20-item questionnaire was administered to collect demographic information, previous disaster experiences, levels of disaster awareness, and attitudes toward disaster medicine. Descriptive statistics were used for data presentation, and the Chi-square test was applied for categorical comparisons. Statistical significance was set at p<0.05. A total of 172 students participated in the study. Among these participants, 80.2% (n=138) stated that they lacked sufficient knowledge regarding the appropriate actions to take during a disaster, and 30.2% (n=52) reported not having received adequate training in disaster preparedness. Among students with previous natural disaster experience, it was observed that such experiences did not significantly impact their knowledge and attitudes towards disaster management (p=0.434). Students who had received training were observed to have greater confidence in providing medical support during disasters (p=0.006). In conclusion, medical students remain a highly motivated but underprepared group in terms of disaster readiness. It is therefore imperative to strengthen their knowledge and skills in disaster management and intervention. Increasing the emphasis on disaster preparedness within medical education programs can better equip students for future disasters and ultimately enhance the overall resilience of the community.
RDL Kalıcı Kaydıİncele - ArticleYalnız künye2025Assessment of vitamin D and iron supplementation practices and their determinants in Erzincan, Türkiye: A cross-sectional study
Hayme, Serhat; Gürsoy, Ersan; Çakır, Hatice; Eren, Salih; Özdemir, Agah; Karabaş, Bilal
Objective: Vitamin D and iron are crucial micronutrients, particularly for children in phases of rapid growth and development, playing significant roles in bone and dental health, immune function, cognitive development, and energy metabolism. Despite the initiation of prophylaxis programs by the Turkish Ministry of Health, adherence and effectiveness remain variable, highlighting the need for localized research to evaluate these initiatives. This study aims to assess the prevalence and continuity of vitamin D and iron supplementation among families in Erzincan, and identify determinants influencing the sustainability of these practices. Methods: A cross-sectional and descriptive study was conducted among 200 families with children aged 1-5 years in the districts of Erzincan. Participants were recruited from family health centers using a convenience sampling method. Inclusion criteria encompassed families with children who met the age requirement, while exclusion criteria included children with special health conditions requiring high-dose supplementation. Data were collected through structured face-to-face questionnaires assessing supplementation practices, sources of medical advice, parental attitudes, and socio-demographic factors. Descriptive statistics summarized the data. The chi-square test and independent samples t-test assessed categorical and continuous variables, respectively. Multiple logistic regression identified factors influencing adherence, while Kaplan–Meier survival analysis evaluated supplementation duration. Results: High rates of vitamin D (98.5%) and iron (94%) supplementation were observed, albeit with decreased adherence to the recommended durations (82.5% for vitamin D, 75.5% for iron). The absence of parental concern for their children’s health and concurrent use of another type of prophylaxis had a positive effect on prophylaxis use. A pediatrician recommended vitamin D and iron prophylaxis to 33% (n=66) of the participants, a family physician to 49% (n=98), and auxiliary health personnel to 3% (n=6) only, whereas 15% (n=32) were advised by more than one health professional. (p=0.008 for vitamin D prophylaxis; p=0.014 for iron prophylaxis). The multivariable logistic regression analyses revealed that parental concern about their infants’ health significantly impacted the continuity of vitamin D prophylaxis (p=0.010). However, demographic characteristics had no significant impact on supplementation practices. Conclusion: Although vitamin D and iron supplementation rates are high in Erzincan, challenges in sustaining recommended durations suggest areas for improvement in prophylaxis programs. This study underscores the importance of healthcare professional recommendations and parental health perceptions in influencing supplementation practices. Recommendations include enhancing health education and accessibility to prophylaxis programs to improve sustainability and adherence.
RDL Kalıcı Kaydıİncele - Review ArticleAçık Erişim2025The Use of Metyrosine in the Treatment of Pheochromocytoma and Paraganglioma Patients: A Review of the Literature
Suleyman, Halis; Babayeva, Mansura; Çakır, Osman Kağan; Huseynova, Gulbaniz
Metyrosine (α-methyl-parathyrosine) functions as an inhibitor of tyrosine hydroxylase, thereby impeding the conversion of tyrosine to 3,4-dihydroxyphenylalanine. This reaction represents the rate-limiting step in the synthesis of catecholamines. This review examines the mechanisms of metyrosine action and its application for treatment purposes. The published literature was collated from a range of scientific databases, including PubMed, SciFinder, ScienceDirect, Wiley Online Library, Google Scholar and Web of Science. The use of metyrosine has been demonstrated to reduce catecholamine biosynthesis in patients with catecholamine-secreting pheochromocytoma and paraganglioma. The safety and efficacy of metyrosine in the treatment of pheochromocytoma and paraganglioma is substantiated by empirical evidence from studies demonstrating its general tolerability and clinical practice use. Metyrosine has been shown to potentially mitigate the occurrence of surgical complications by enhancing intraoperative hemodynamics. Studies have demonstrated that the administration of metyrosine prior to pheochromocytoma and paraganglioma surgery reduces the risk of hypertensive crisis and severe hypertension, as well as intraoperative haemodynamic variability. It is imperative that further research is conducted to elucidate the pharmacokinetics, intricate molecular mechanisms, and safety profile of methyrone. To this end, the utilization of meticulously designed randomized clinical trials is crucial.
RDL Kalıcı Kaydıİncele - ArticleAçık Erişim2025Assessing the knowledge and practices of family physicians in eye screening and early diagnosis
Gürsoy, Ersan; Gürsoy, Nurcan; Vatansever, Mehmet; Nas, Mehmet Akif
This study aimed to evaluate family physicians’ knowledge and practices in primary healthcare settings. It focused specifically on their approaches to eye screening, early diagnosis, and management of eye diseases. This descriptive, cross-sectional study was conducted among family physicians working in the provinces of Erzincan, Trabzon, and Erzurum. Data were collected between September and December 2024 using a 37-item questionnaire developed through a literature review and pilot testing. The questionnaire, delivered via Google Forms, included Likert-scale items covering demographic information, eye screening practices, and knowledge levels. Data were analyzed using descriptive statistics, the Kolmogorov–Smirnov test, Kruskal–Wallis test, Mann Whitney U, and Spearman correlation analysis. A total of 124 family physicians participated in the study. While 40.3% reported performing red reflex screening only for infants aged 0–3 months, 29.8% stated they did not perform it at all. Additionally, 21.8% indicated that a direct ophthalmoscope was either unavailable or its availability was unknown at their centers. The mean knowledge score was 58.15, with male physicians scoring significantly higher than female physicians (p=0.023). No significant associations were found between knowledge scores and age, total professional experience, or job title. However, a positive and significant correlation was identified between the duration of family medicine practice and knowledge level (r=0.240, p=0.007). The findings revealed notable deficiencies in the knowledge and practices of family physicians concerning eye health screening and early diagnosis. To enhance the quality of primary eye care, it is essential to implement regular training programs, ensure the availability of ophthalmic examination tools, and establish national screening protocols. This study contributes foundational insights to strengthen the role of family physicians in the early detection and management of eye conditions.
RDL Kalıcı Kaydıİncele - ArticleAçık Erişim2025Effects of Selective Serotonin Reuptake Inhibitor Treatment on Blood Pressure in Resistant Hypertensive Patients with Anxiety Disorder
Vatansever, Mehmet; Çakır, Osman Kağan
Objectives: This study aimed to evaluate the effects of selective serotonin reuptake inhibitor (SSRI) treatment on blood pressure (BP) control in resistant hypertensive patients with anxiety symptoms. Methods: This interventional study was conducted between January 2021 and March 2022 at a family medicine outpatient clinic. Patients with primary hypertension (HT), uncontrolled with monotherapy, and scoring ≥16 on the Beck anxiety inventory were included. All were switched to combination antihypertensive therapy. Those who accepted SSRI treatment constituted the case group, while those who declined formed the control group. Demographic and clinical characteristics were recorded. BP was measured at baseline and after 1 month. Results: Ninety-one patients were included, 30 (33.0%) male, the median age was 53.5 (35.0–68.0) years. Of the participants, 72 (79.1%) received combined therapy plus SSRI, while 19 (20.9%) received combined therapy only. After 1 month, systolic BP decreased by 15.0 (1.0–22.0) mmHg and diastolic BP by 13.0 (4.0–18.0) mmHg in the case group, compared to decreases of 8.0 (1.0–17.0) mmHg and 6.0 (2.0–13.0) mmHg in the control group (respectively, p<0.001 and p<0.001). Conclusion: SSRI therapy provided significantly greater reductions in both systolic and diastolic BP compared with combination antihypertensive treatment alone. Anxiety should be considered an important factor in resistant HT, and psychological as well as pharmacological interventions may enhance treatment outcomes.
RDL Kalıcı Kaydıİncele
Tam Kayıt
| Alan | Değer | Dil |
|---|---|---|
| dc.date.accessioned | 2026-10-20T15:26:05.206034822Z | |
| dc.date.available | 2026-10-20T15:26:05.206034822Z | |
| dc.identifier.uri | https://rdlopen.rawdatalibrary.net/r/ebyu/22874 | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.title | Aile Hekimliği Anabilim Dalı | tr |
| dc.title | Department of Family Medicine | en |
| dspace.entity.type | OrgUnit | |
| organization.identifier.code | tip-aile-hekimligi | |
| organization.unitType | department | |
| rdl.unit.alias | \bfamily (med|pract|phys) |