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- Suleyman, Halis(167)
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Yayınlar
- MakaleAçık Erişim2019Morphometric Evaluation of Craniocervical Junction by Magnetic Resonance Imaging Method
Sunar, M; Kapakin, S
- MakaleAçık Erişim2019Effects of melatonin treatment on the spermatogenesis and serum inflammatory cytokine levels in diabetic rats
Erol, Huseyin Serkan; Terzioğlu, Merve Aydın; Onk, Didem; Gürsul, Cebrail; Gumustas, Sinem; Bozkurt, Aliseydi; Karabakan, Mehmet
Aim: Diabetes mellitus (DM) is known to have side effects on sexual and reproductive functions in males. The aim of current study was to investigate the effect of melatonin treatment on spermatogenesis and serum inflammatory cytokine levels in diabetic rats.Material and Method: Eighteen adult Wistar albino male rats were divided randomly into three groups each containing 6 rats; control group (group 1), diabetic group (group 2), diabetic treated with melatonin group (group 3). Experimental diabetes was obtained by administrating 50 mg/kg streptozotocin. Melatonin treatment was administered intraperitoneally for 7 days at a dose of 20 mg, daily. Serum levels of interleukin-1 beta (IL-1β), interleukin 6 (IL-6) and tumor necrosis factor-alpha (TNF-α) were assayed. Spermatogenesis was evaluated according to Johnsen score at immunopathological examination.Results: The Johnsen scores in control, diabetic and treatment groups were 9.78, 8.91, and 9.61, respectively. Spermatogenesis was negatively affected in diabetic rats and significantly improved with melatonin therapy (p<0.05). The serum levels of TNF-α in diabetic rats were observed to be increased compared to the control group (p<0.05). The levels of serum IL-1β and TNF- α were significantly decreased with melatonin treatment. IL-6 levels were not different among the three groups (p=0.248).Conclusions: In the present study, intraperitoneal melatonin treatment was determined to have a positive effect of on spermatogenesis and caused a decrease in serum inflammatory cytokine levels in diabetic rats.
- MakaleAçık Erişim2019How to prevent unnecessary request prostate-specific antigen testing?
Mertoğlu, Cuma; Bozkurt, Aliseydi
Aim: In this study, it was aimed to show how to limit the unnecessary requests of free prostate-specific antigen (fPSA) test changes with some regulations.Material and Methods: The fPSA requirements when total PSA values below 4 ng/mL or above 10 ng/mL were considered ‘unnecessary test request’. To do this, the relevant physicians were informed and the fPSA test was arranged to have a separate second window on the request panel and physicians were requested only tPSA test requests. An additional fPSA test was conducted by the laboratory staff from patients with a tPSA score of 4-10 ng / mL.Results: It was seen that 1236 fPSA and 1292 tPSA tests (fPSA/tPSA = 95.6%) were performed in our research hospital laboratory between January 17,.2017 and March 09,2017 while 328 fPSA and 1139 tPSA tests were also done between January 17, 2018 and March 09, 2018 (fPSA / tPSA = 28.7%). The ratio of sPSA test request to tPSA test request was found to be reduced by 66.9%.Conclusion: This study limited significant hospital expenditure and labor loss reducing the number of unnecessary fPSA tests with regulations made at the test prompt.
- MakaleAçık Erişim2019The value of standard chest radiography in the diagnosis of scoliosis
Üçpunar, Hanifi; Kockara, Nizamettin
Aim: The aim of this study was to evaluate the benefits and limitations of chest radiographs in scoliosis screening and to compare these results with spine orthoroentgenogram.Material and Methods: We performed a retrospective, repeated cross-sectional evaluation of 5160 digital standing posterior-anterior chest x-rays of patients, ages from 21 to 44 years old, obtained at our institution. The chest radiography was taken to the hospital for military check-ups. All posterior-anterior chest radiographs between January 2016 and December 2017 were gathered. We compared the spinal curvature types and Cobb angles detected in the chest radiographs (n=62) with the curvature types and Cobb angles detected on spine orthoroentgenogram radiographs.Results: According to the type of major spinal curvature, overall matching of chest x-ray with the radiography of the spine orthoroentgenogram was 71% (44 of 62 cases). Measured mean Cobb angle on the chest x-rays and spine orthoroentgenogram was 9.8 (5.4) and 12.8 (6.5) respectively (p=0.009). Chest radiographs were 81% sensitivity and 50% specificity according to spine orthoroentgenogram, which was accepted as the gold standard in the diagnosis of scoliosis according to the spinal curvature.Conclusions: The data obtained in our study can be considered as a valuable reference in the consultation of asymptomatic thoracic scoliosis detected on the routine chest radiograph and the necessity of examination of the axial skeletal with spine orthoroentgenogram.
- MakaleAçık Erişim2019The clinical outcomes of intravitreal dexamethasone implant as the first-line treatment in retinal vein occlusion related macular edema
Karakurt, Yucel
Aim: To investigate the alterations in central macular thickness (CMT), best-corrected visual acuity (BCVA) and intraocular pressure (IOP) after intravitreal dexamethasone implant (IDI; Ozurdex) injections in patients with treatment-naive central retinal vein occlusion (CRVO) and branch retinal vein occlusion (BRVO)-related macular edema in clinical practice.Material and Methods: Totally 41 eyes of 41 patients diagnosed with BRVO or CRVO, who were treatment-naive and treated with only intravitreal dexamethasone implants, were retrospectively investigated. Anterior and posterior segment examinations were performed with a slit lamp bio-microscope. BCVA was assessed using Snellen chart and then converted to logarithm of minimum angle of resolution (log MAR) units before statistical analysis and CMT measurements were performed with spectral domain optical coherence tomography.Results: The mean age of patients was 65.95 ±6.164 years (range: 51-78). Central retinal vein was occluded in 14 patients while branches were occluded in remaining 27 patients. The patients were followed for 14.93±1.942 months (median: 15, range: 12-20 months). The mean number of injections was 2.83±0.803 (median: 3, range: 1-4). BCVA was significantly better in all time periods after treatment (p: 0.001). There was a significant decrease in CMT in all time periods after treatment compared with pre-treatment values (p: 0.001). During follow-up period, IOP was determined to be higher than 25 mm-Hg in 5 patients, and cataract was diagnosed in 6 patients.Conclusion: Intravitreal dexamethasone injection is an effective mode of treatment in patients with RVO-associated macular edema. Its side effects are not severe or common. However the patients should be kept under follow-up for recurrences.
- MakaleAçık Erişim2019Comparison of the clinical efficacy and safety of deep sclerectomy with mitomycin-c and trabeculectomy surgerie
Mesçi, Cem; Erbil, Hasan Hasbi; Gomceli, Senem Salar; Acar, Hüseyin; Karakurt, Yucel
Aim: Comparison of clinical efficacy and safety of trabeculectomy and deep sclerectomy with mitomycin-C (MMC) surgeries.Material and Methods: 58 eyes of 58 patients with glaucoma who underwent trabeculectomy or deep sclerectomy with MMC were evaluated retrospectively. The success criterion was regarded as follows; patients having intraocular pressure (IOP) less than 21 mmHg was regarded as complete success; patients with IOP less than 21 mmHg with medication was regarded as partial success; and patients with IOP higher than 21 mmHg with medication was regarded as un-success.Results: There was no statistically significant difference in IOP lowering effects between the two surgeries. Considering the success of the groups; complete success was achieved in 32 patients (91.4%) and partial success in 3 patients (8.6%) in the trabeculectomy group. Complete success was achieved in 20 patients (86.9%) and partial success in 3 patients (13.1%) in the deep sclerectomy with MMC group. In the deep sclerectomy with MMC group, hypotonia was detected in 2 patients (8.7%). In the trabeculectomy group, 5 patients (14.3%) had hypotonia, 2 patients (5.7%) had shallow anterior chamber and 1 patient (2.85%) had choroidal detachment.Conclusion: When IOP lowering effects of deep sclerectomy with MMC and trabeculectomy operations were compared, it was found that there was no statistically significant difference between the two techniques. When complication rates were compared, less complication was found in deep sclerectomy operations. It can be concluded that deep sclerectomy is safer than trabeculectomy and as effective as it is.
- MakaleAçık Erişim2019The findings of corneal specular microscopy in patients with keratoconus
Arslan, Yusuf Kemal; Agcayazi, Sumeyye Burcu; Ucak, Turgay; Uğurlu, Adem; İçel, Erel; Taşlı, Nurdan Gamze; Karakurt, Yucel
Aim: The aim of this study was to determine the correlation of corneal endothelial cell density, coefficient of variation and hexagonal cell ratio with the stages of keratoconus and corneal thickness.Material and Methods: The study included 102 eyes from 51 patients. The corneal topography was performed using the Sirius corneal topographic device and the examination of the endothelium was performed using Nidek CEM-530. The patients were divided into groups in accordance with keratometry values (group 1: K2<45 D, group 2: K2 45-52 D, group 3: K2> 52 D) and thinnest cornea thickness (group 1:> 450 μm, group 2: 400-450 μm, group 3: <400 μm). Specular microscopic findings were compared according to the severity of keratoconus and corneal thickness.Results: Of the patients, 29 (50%) were male and 22 (50%) were female. The mean age was 29.8 ± 7.7 (15-45) years. Endothelial cell count and hexagonal cell ratio were significantly lower in severe keratoconus compared to mild and moderate keratoconus and the coefficient of variation was higher in severe keratoconus compared to the other groups (p <0.001). When the patients were compared according to the pachymetry value at the thinnest point of the cornea, the endothelial cell number and the hexagonal cell ratio were found to be lower in the group with pachymetry less than 400 μm (p <0.001). The coefficient of variation was higher in the same group compared to the others (p <0.001).Conclusion: It was revealed that endothelial cell density, hexagonal cell ratio decreased and the coefficient of variation increased with the progression of keratoconus. Specular microscopic examinations in patients with keratoconus provide important data in addition to topography.
- MakaleAçık Erişim2019Anterior segment parameters and corneal specular microscopy findings in rheumatoid arthritis
Agcayazi, Sumeyye Burcu; Ucak, Turgay; Yılmaz, Hayati; İçel, Erel; Taşlı, Nurdan Gamze; Karakurt, Yucel; Aktaş, Nurdagül
Aim: To compare the anterior segment parameters and specular microscopy findings between patients with Rheumatoid arthritis(RA) and healthy controls.Material and Methods: In this prospective study, 55 patients diagnosed with RA and age and matched 55 control subjects without anysystemic diseases were enrolled. Central corneal thickness (CCT), corneal endothelial cell density (cells/mm2) (ECD), percentage ofhexagonal cells of corneal endothelial cells ( HEX), and cell size variability (CV%) of endothelial cells were measured using noncontactspecular microscopy (CEM-530 Specular Mıcroscope, NIDEK ).Anterior chamber depth (ACD), Axial Length (AL), white to white limbus length and keratometry were measured using an ocularbiometry system. In all patients of RA group, disease activity severity was assessed with The Disease Activity Score in 28 jointsdiseases activity score (DAS28 rate).Results: There were statistically significant differences between RA patients and control subjects regarding ACD (3.06±0.43 vs3.24±0.31; p: 0.001), white to white limbus length (11.63±0.45 vs 11.76±0.38; p: 0.02), CV% (35.49±5.96 vs 32.02±5.22, p: 0.001)and hexagonality (67.31±4.66 vs 71.35±11.02; p: 0.001). In correlation analysis, there was a negative correlation between diseaseperiods and both ACD and CCT; while there was a negative correlation with the number of cells and endothelial cell density and DAS28 score.Conclusion: Although there was not a significant difference regarding endothelial cell density values in RA group compared withhealthy controls; there was a negative correlation between the disease activity and endothelial cell density. Moreover, CV% wassignificantly higher and hexagonality % was significantly lower in RA group; indicating the endothelial damage and increase in theexpected compensatory response.Further, larger studies are warranted to define the exact pathological mechanisms and clinical outcomes of this corneal endothelialdamage in RA patients.
- MakaleAçık Erişim2019Evaluation of the effect of chronic smoking habit on corneal endothelial cells, central corneal thickness and dry eye tests
Agcayazi, Sumeyye Burcu; Ucak, Turgay; Uğurlu, Adem; İçel, Erel; Taşlı, Nurdan Gamze; Karakurt, Yucel; Sunar, Mukadder
Aim: The aim of our study was to evaluate the effects of chronic smoking habit on corneal endothelial cells, central corneal thickness,and dry eye tests.Material and Methods: A total of 160 eyes of 160 chronic smokers and 160 eyes of 160 control cases were included in the study. Thesmokers were grouped into 4 groups according to pack-year smoking as follows: 0-10, 10-20, 20-30, >30. Endothelial cell density(CD), average cell size (AVG), percentage of hexagonal cell (HEX), and coefficient of variation (CV), central corneal thickness (CCT)were measured using a specular microscope. The Tear Break-Up Time (TUBT) and Schirmer tests were performed.Results: In Group 1 and Group 2, there was no significant difference between the smoker and the control groups in terms of CD, AVG,HEX and CV. In Group 3 and Group 4, there was a significant decrease in CD and HEX values, while there was a significant increasein AVG and CV values. CCT values were not significantly different in the Groups 1,2 and 3, whereas there was a significant decreasein the Group 4. TBUT and Schirmer tests were significantly decreased in all groups.Conclusion: It was found that as the number of pack-year increased, CD and HEX values decreased and AVG and CV values increased.Dry eye tests were affected in a shorter period of time, while CCT was affected in a longer period of time than the time required forCD, HEX, AVG and CV parameters to be affected.
- MakaleAçık Erişim2019Diagnostic errors in computed tomography outsourcing: Analysis of a single center
Karavaş, Erdal; Hirik, Erkan
Aim: The reporting of medical imaging with outsourcing is used by many hospitals in Turkey. The aim of this study was to evaluateoutsourced computed tomography (CT) reports and determine any errors made.Material and Methods: The study was planned with a prospective design. The reports of the CT tests taken during 2017 by anoutsourced company of 35 randomly selected patients were compared. In the comparison, findings which could lead to a change indiagnosis and treatment were labelled as “significant” and findings which would not lead to a change in diagnosis and treatment werelabelled as “non-significant”. Findings reported in the study comparison but not mentioned or written incorrectly in the outsourcedcompany report were classified as “absence” and any finding that was written but not present was labelled as “extra”.Results: The study included the examsimages and reports of 35 patients, comprising 18 (51.4%) males and 17 (48.6%) females witha mean age of 49.37± 23.66 years. A major error was found in 27 (77%) cases. No statistically significant difference was determinedin the significant, non-significant, absent and extra data according to patient age (p>0.05).Conclusion: There should be an implementation of regulations for clinicians to be able to re-use the diagnostic algorithm. Residentialemployment of radiologists should be encouraged rather than outsourcing.
- MakaleAçık Erişim2019A cost minimization analysis of intracameral cefuroxime and moxifloxacin in cataract surgery
Bozkurt, Erdinç; Çelik, Erkan; Çüçen, Bülent; Ucak, Turgay; Atum, Mahmut; Yuvacı, İsa; Doğan, Emine
Aim: In this study, we aim to perform Cost Minimization Analysis of cefuroxime and moxifloxacin, which have proven to have a similarefficacy in the prophylaxis of endophthalmitis after cataract surgery.Material and Methods: The records of 1097 patients who had undergone cataract surgery and intracameral antibiotic (cefuroxime,moxifloxacin) injection in 2018 were evaluated retrospectively. Patients undergoing cataract surgery were divided into two groupsaccording to the type of antibiotic injected into the anterior chamber. Group 1 consisted of patients who received intracameral1mg/0.1ml cefuroxime and Group 2 consisted of patients who received intracameral 500 μg /0.1ml moxifloxacin. In the postoperativeperiod, patients in both groups received topical antibiotic drops containing 0.5% moxifloxacin and steroid drops containing 0.1%dexamethasone for 7 days.Results: The Group 1 consisted of 213 (19.4%) patients, of which 97 (45.5%) were male and 116 (54.5%) were female, while Group 2consisted of 884 (80.6) patients, of which 439 (49.7%) were male, and 445 (50.3%) were female (p=0.280). The groups were similarin terms of age and gender distribution of the patients. There was no significant difference in terms of the posterior capsule rupturedevelopment between the two groups (p=0.692).BCVA was statistically significant before and after surgery in both groups. None ofthe patients in both groups developed endophthalmitis. The cost of the drugs used in the first group was 3 times higher than thesecond group.Conclusion: The antibiotics injected to the anterior chamber during cataract surgery have similar effectiveness, moxifloxacin injectionto the anterior chamber was found to be more advantageous in terms of cost, compared to the use of disposable cefuroxime.
- MakaleAçık Erişim2019Transitional cell carcinoma of the bladder in young adult patients
Karabulut, İbrahim; Keskin, Ercüment; Erdoğan, Abdullah
Aim: Transitional cell carcinoma of the bladder (TCC) mostly affects the middle and old population as in other cancers. We aimed to present the results and clinical behaviors of patients treated with bladder TCC under the age of 40 years.Material and Methods: Fifteen patients who were admitted to our clinic between 2005 and 2019 and diagnosed as TCC were evaluated retrospectively. Demographic characteristics, initial and follow-up transurethral resection pathologies, intravesical treatment and follow-up periods were evaluated. All patients underwent transurethral resection after ultrasonography (USG) and cystoscopy examination.Results: The most common complaint was macroscopic hematuria (n:12.80%).Smoking rate was 66% (n:10). The mean age of the patients was 32.4 (19-39). Male / female ratio was 13/2. The mean follow-up period was 55 weeks. Ten patients (66%) had single focus and five (34%) had multiple focus tumors. In 10 patients, the tumor pathology TaG1, TaG3 in 3, T1G1 in one and T1G3 in one patient were reported.4 patients received intravesical chemotherapy and four patients underwent intravesical immunotherapy (BCG). The recurrence rate was 53% (n:8) and the rate of pro- gression was 13% (n:2) (TaG1-T1G3). None of the patients progressed to T2 disease.Conclusuion: Bladder TCC under 40 years of age usually presents as TaG1. Survival rates are high if follow-up and treatment protocols are followed. It should be kept in mind that there may be bladder tumors in young adult patients regardless of age.
- MakaleAçık Erişim2019The effect of sleep quality on academic performance
Topal, İsmail
Aim: Sleep problem is a common issue among children. Insufficient sleep leads to inattention and behavior disorders and thus adversely affects academic performance. In this study, it is aimed to research the effect of sleep quality on the academic performance of eighth-grade students who are going to take the national exam (TEOG) designed for the transition to secondary education from primary education.Material and Methods: Population of the research consists of 272 8th grade students attending eight different schools in Erzincan province. Pittsburgh Sleep Quality Index (PSQI) was applied in research questionnaire and Bodymedia’s Armband Sense Wear Metabolic Holter (SWA) device was utilized to measure sleep effectiveness.Results: It is found that TEOG scores of the students, whose PSQI score <5 and who has a high sleep quality measured by the Bodymedia’s Armband Sense Wear Metabolic Holter, are high.Conclusion: Students who have a good quality of sleep have better academic performance in the school. Body Media Sense Wear Metabolic Holter is an effective and practical method to measure sleep quality.
- MakaleAçık Erişim2019Association between biomarkers in the long-term prognosis of ischemic stroke
Bilge, Nuray; Ceylan, Mustafa; Yalçın, Ahmet; Gundogdu, Omer Lutfi
Aim: Predicting of the stroke prognosis has utmost importance as the disease has a heavy socioeconomical burden. For thisreason, instruments such as stroke severity scales, stroke volume calculations and various biomarkers are used for determinationof prognosis. NIHS scale, stroke volume, stroke type, neutrophil/lymphocyte ratio and C-reactive protein levels were reported to beassociated with stroke prognosis. In this study we aim to investigate the relationship between these parameters with 8-year-survivalfrom stroke.Materials and Methods: Between January 2010 and January 2012, all patients aged over 18 and diagnosed with arterial stroke wereretrospectively investigated. Data regarding survival status were obtained from Death Reporting System (https://obs.gov.tr/) underthe surveillance of Ministry of Health. NIHS scale, stroke volume, stroke subtype, neutrophil/lymphocyte ratio and C- reactive proteinlevels were obtained and compared in deceased and living patients and association between those parameters and survival wassought.Results: Advanced age, male gender, NIHS scale, stroke volume, stroke subtype, neutrophil/lymphocyte ratio were associated withstroke survival. C-reactive protein levels were not be found associated.Conclusion: Our results were consistent with the literature and, NIHS scale, stroke volume, stroke subtype, neutrophil/lymphocyteratio predicted the stroke prognosis. As there is not enough data present in the literature, our findings were remarkable.
- MakaleAçık Erişim2019Analysis of genomic stability and DNA damage in plants exposed to cement dust pollution using the RAPD analysis
Ertürk, Filiz Aygün; Agar, Guleray; Sunar, Serap
One of the most important environmental pollutants is cement dust. In this study, RAPD technology was used todefine the potential genotoxic impact of cement dust on plants. For this purpose, the DNA comparison of 12 plant species(Convolvulus sepium, Astragalus christianus, Taraxacum androssovii Medicago varia, Alyssum murale, Artemisiaspisigera, Falcaria vulgaris, Anchusa strigose, Glaucium leiocarpum, Salvia syriaca, Cryciata taurica Tragopogonalbinervis)collected from the areas of 10000 m (Control area) or 0-100 m away from Askale cement factory in Erzurum;was performed. 16 primers were used, and 390 bands were obtained. Important differences were observed in plant RAPDprofiles collected from 0-100 m areas when compared to their respective controls (10000 m away from the factory). Somebands in control plants got lost, and new band formations were observed. The Genomic template stability (GTS) valuedecreased significantly in plants collected from 0-100 m area as compared to the controls (%56.20). Soil samples from 0-100 m and control area were collected and examined for their heavy metal contents. According to the analysis results,Nickel, Cadmium, Zinc, Lead and Copper concentrations were found to be dramatically high in the soil collected from 0-100 m as compared to the control area. These results indicate that the high heavy metal content in the soil causes thechanges in RAPD profiles and GTS in plants. The data also indicated that RAPD and GTS assays are basic, effective andreproducible means of the genotoxicity control of environmental pollution.
- MakaleAçık Erişim2019Comparison of AIMS65 and rockall scoring systems for predicting mortality in patients with upper gastrointestinal system hemorrhage
Davarci, Ismail; Davarci, Pinar Zehra; Sazli, Hulya
Aim: Acute upper gastrointestinal system hemorrhage is a common and life-threatening condition, and its mortality may reach 10%despite developing medical facilities. In this study, we aimed to compare the efficacy of the AIMS65 risk scoring and Rockall scoringin the non-variceal upper gastrointestinal hemorrhage patients and investigate the relationship between C-reactive protein/albuminratio and these scoring systems.Materials and Methods: Forty-two inpatients diagnosed with upper gastrointestinal system hemorrhage in our hospital’s InternalMedicine Department between January 2018 and July 2018 included to study. For each patient, AIMS65 scoring according to the firstevaluation results in the emergency department and Rockall scoring after the endoscopy were performed.Results: Mortality was observed in 2 (4.8%) patients. Both scoring systems were not statistically significant in determining the needfor transfusion and predicting the hospitalization duration. The mean C-reactive protein/albumin ratio of the patients was found tobe 0.94 (0.48-77.83), and C-reactive protein/albumin levels were higher in patients with high AIMS65 score (p=0.005).Conclusion: Upper gastrointestinal hemorrhage is a common emergency problem, and it constitutes 80% of all gastrointestinalsystem hemorrhages. In our study, the C-reactive protein/albumin ratio was consistent with the AIMS65 score and suggested thatit could be a parameter that could be used in patients with upper gastrointestinal system hemorrhage, but more extensive studiesare needed on this subject.
- MakaleYalnız künye2019Günaşımı olan, nullipar gebelerde prostaglandin e 2 'nin doğum indüksiyonu üzerine etkisi
Turkler, Can
Amaç: Bu çalışmanın amacı, hastanemizde son iki yılda prostaglandin E 2 (dinoproston) ile doğum indüksiyo-nu uygulanan günaşımı ve nullipar gebelik olgularının epidemiyolojik ve klinik olarak değerlendirilmesidir.Gereç ve Yöntem: Çalışmamda gün aşımı (gebelik haftası ≥ 41 hafta) nedeniyle dinoproston ile doğumindüksiyonu almış 136 nullipar gebe değerlendirildi.Bulgular: Dinoproston uygulanan günaşımı ve nullipar gebelerde sezaryenle doğum oranı % 31.6 olarakbulundu. Dinoproston indüksiyonu sonrası vajinal doğum (NVD) yapanlarla dinoproston sonrası sezaryendoğum (C/S) yapan hastalar kıyaslandı. Fetal distres (% 48.8), ilerlemeyen eylem (% 32.5) ve sefalopelvikuyumsuzluk (% 18.6), sezaryenle doğumlarda en sık görülen endikasyonlardı. Postpartum dönemde yenido-ğan yoğunbakım ihtiyacı oranları, normal doğum yapanlarda % 3.2, sezaryenle doğum yapanlarda % 4.6 idive her iki grup için de benzerdi.Sonuç: Dinoproston, nullipar gebelerde servikal olgunluğu sağlamak ve doğum indüksiyonu için kullanılangüvenilir ve etkili bir ajandır. Fetal distres sebebiyle sezaryen oranlarını arttırmaktadır.
- MakaleAçık Erişim2019Raşitizmden Korunmada Güneş Işığına Yönelik Annelerin Yaptıkları Uygulamaların Belirlenmesi
Bekar, Pınar; Arıkan, Duygu
Amaç: Çocuklarının raşitizmden korumak için güneş ışığına maruz kalmalarına yönelik annelerin yaptıkları uygulamaların belirlenmesidir. Gereç ve Yöntemler: Araştırma, Türkiye’de bulunan birüniversite hastanesinde tanımlayıcı nitelikte yapılmıştır. Araştırmanın evrenini 2016 Nisan-2017 Aralık tarihleri arasında 0-2 yaşındaki çocuğu hastanede yatan, ulaşılabilen tüm anneler oluşturmuş; herhangi bir örneklem seçim yöntemine gidilmeden, uygulamanın yapıldığı zamanda hastanede olan,seçilme kriterlerine uyan ve araştırmaya katılmak isteyen 169 anne araştırmanın örneklemini oluşturmuştur. Çalışma kapsamına 18 yaş ve üstü olan, kognitif ve bilişsel fonksiyonları iyi olan, iletişim kurulabilen, 0-2 yaşında çocuğu olan ve araştırmaya katılmaya istekli anneler alınmıştır. Araştırmada, verilerliteratürden yararlanılarak geliştirilen anket formu ile hastanede annelerle yüz yüze görüşülerek toplanmıştır. Etik kurul ve araştırmanın yapılacağı hastaneden yazılı, annelerden sözel ve yazılı izin alınmıştır. Verilerin değerlendirilmesinde yüzdelik ki-kare testi analizi yapılmıştır. Bulgular: Annelerin%76,9’unun çocuğunu güneşe çıkarttığı, güneşe çıkan çocukların %48,5’inin genelde günde bir kez güneşe çıkarıldığı ve güneşe çıkanların %73,8’inin güneş ışığını direkt aldığı saptanmıştır. Çocuğun yaşı arttıkça güneş ışığını direkt alan çocuk sayısı artmaktadır. Çocuğun yaşına göre güneş ışığını alma şekli,aldığı bölgelerin etkilendiği saptanmıştır. Annenin eğitim durumunun çocuğun güneş ışığını alma şekli,aldığı bölgeleri etkilemediği bulunmuştur. Çocukların hiçbirinde raşitizm görülmemiştir. Sonuç: Çocukların tamamına yakını D vitamini almakta, çoğu güneşe çıkartılmakta ve raşitizm olan çocuk bulunmamaktadır. Annenin eğitim durumunun çocukların güneş ışığına maruz kalmasına etkisi olmadığısaptanmıştır. Çocukların güneş ışığını alması raşitizm açısından önemlidir.
- Derleme MakaleAçık Erişim2019Yaşlanma ve Sirkadiyen Ritmin Moleküler Mekanizmaları
Kiyan, Toros; Findik Kiyan, Hilal
Organizmalar 24 saatlik gündüz-gece döngüsüne adapte olmuşlardır. Bu sirkadiyen ritimler,fizyolojik ve metabolik süreçleri kontrol eden içsel bir hücresel mekanizma tarafından üretilmişlerdir. Bilindiği üzere, yaşlanma sürecinde sirkadiyen sistem zayıflamakta ve biyolojik değişimleryavaşlamaktadır. Sirkadiyen genlerin genetik olarak değişimi ve moleküler saatin bozulması yaşlanma süreciyle ilişkilidir. Ayrıca çevresel koşullar da (Örneğin; kalori kısıtlaması) yaşlanma sürecine etki eden önemli faktörlerdendir. Besinsel sensörleri içeren hücre içi yolaklar, yaşlanmasürecini kontrol eden hücresel ve epigenetik mekanizmaları etkilemektedirler. Yapılan çalışmalarla bu yolakların hem yaşlanma sürecinin düzenlenmesinde hem de moleküler saatin kontrolündegörev aldığı gösterilmiştir. Bu nedenle, sirkadiyen saatin ve besin algılama yolaklarının kontrolüneyönelik terapötik stratejiler, yaşlanma sürecindeki olumsuz etkileri azaltarak, bu sürecin daha verimli olmasını sağlayacak gibi görünmektedir.
- MakaleAçık Erişim2019Diyabete Eşlik Eden Ruhsal Sorunlar ve Diyabet Yönetimi
Çayköylü, Ali; Hacıhasanoğlu Aşılar, Rabia; Yildirim, Arzu; Çapoğlu, İlyas
Diyabet, günümüz toplumlarını önemli düzeyde etkileyen bir toplum sağlığı sorunu olup bulaşıcı olmayan salgın bir hastalık olarak belirtilmektedir. Ruhsal etkenler, iyi glisemik kontrolün sürdürülmesinde önemlidir. Başta depresyon olmak üzere ona eşlik eden ruhsal sorunlar özbakımda olumsuz bir etkiye sahip olup bu durum kötü glisemik sonuçlar ve artan komplikasyon riski ile ilişkilidir. Bu nedenle sağlık profesyonelleri diyabet yönetiminde ruhsal sorunları göz ardı etmemeli, özellikle depresif hastalarda özkıyım riskinin farkında olmalıdırlar. Diyabet öz yönetiminin temel unsurları: eğitim, diyet, izlem, yaşam biçimi ve tedaviye uyumdur. Öz yönetim önlemlerinin sürdürülmesi yüksek motivasyon gerektirmekle birlikte hastaların çoğu, özellikle ruhsal ve toplumsal sorunlar yaşayanlar öz yönetim stratejilerini zorlayıcı bulabilmektedir. Bu yazıda: diyabet, diyabet yönetimi, diyabette ruhsal bozuklukların doğası ve diyabet yönetiminin hasta sonuçlarına etkisi ele alınmaktadır. Ayrıca uygulanabilir stratejiler ve birey odaklı bütüncül bir yaklaşım içerisinde diyabet öz yönetim eğitimi ve desteği ile hastanın kendi bakımında aktif rol üstlenmesini sağlayan işbirlikçi ve çok disiplinli ekip çalışmasının önemi vurgulanmaktadır.
